Clozapine Impurity 21 CAS CATO-C4X-134021
| CAS No. | CATO-C4X-134021 |
| Molecular Formula | C20H14ClN3O5 |
| Molecular Weight | 411.80 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Clozapine Impurity 21 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Clozapine Impurity 21 (CAS CATO-C4X-134021) is a certified pharmaceutical impurity reference standard with the molecular formula C20H14ClN3O5 and a molecular weight of 411.80 g/mol.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Clozapine Impurity 21 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 411.80 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C20H14ClN3O5 |
| Molecular Weight | 411.80 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | ≥95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Clozapine Standards
- Clozapine Impurity 14 (CAS 1025951-76-1)
- Clozapine Impurity 15 (CAS 156632-03-0)
- Clozapine EP Impuirty C-D8 N-nitroso (CAS CATO-C4X-134018)
- Clozapine EP Impurity D (CAS 65514-71-8)
- Clozapine N-Oxide (CAS 34233-69-7)
- Clozapine Impurity 22 (CAS CATO-C4X-134022)
- Clozapine-d8 (CAS 1185053-50-2)
- Clozapine-D4 (CAS 204395-52-8)
Recommended Standards
- Toxaphene (CAS 8001-35-2)
- Ipfentrifluconazole (CAS 1417782-08-1)
- 3-(4-Chlorophenyl)-N-(2,4-difluorophenyl)-4-oxo-3,4-dihydrophthalazine-1-carboxamide (CAS 320417-63-8)
- (Z)-1-(3-(pyrrolidin-1-yl)-5-(trifluoromethyl)pyridin-2-yl)ethan-1-one O-(4-chlorobenzoyl) oxime (CAS 860611-43-4)
- Salcaprozate Impurity 3 (CAS CATO-C4X-25073)
- Mirogabalin Impurity 179 (CAS CATO-C4X-2924179)
- Droxidopa Impurity 2 (CAS 5707-55-1)
- Methyl (1s,4s)-4-(aminomethyl)cyclohexane-1-carboxylate hydrochloride (CAS 916211-57-9)
- (R)-Hexan-2-ol (CAS 26549-24-6)
- (E)-1-(3-chloroprop-1-en-1-yl)-3-methoxybenzene (CAS 478930-89-1)
- 4-(3-(2,4-Dichlorophenyl)-[1,2,4]triazolo[4,3-c]quinazolin-5-yl)morpholine (CAS 338977-91-6)
- tert-Butyl 3,3-dimethyl-2-oxobutylcarbamate (CAS 1330753-92-8)
- 5-((4-Fluorophenoxy)methyl)furan-2-carbohydrazide (CAS 438221-91-1)
- Peptide 432 (CAS CATO-CPTD788432)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com