Famotidine Impurity 50 CAS 95853-51-3

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.95853-51-3
Molecular FormulaC5H8N4S2
Molecular Weight188.27 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Famotidine Impurity 50 CAS 95853-51-3 chemical structure

Description

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Famotidine Impurity 50 (CAS 95853-51-3) is a certified pharmaceutical impurity reference standard with the molecular formula C5H8N4S2 and a molecular weight of 188.27 g/mol.

The molecular framework of Famotidine Impurity 50 (C5H8N4S2) is characterized by a nitrile group, sulfur-containing functionality. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

Physical & Chemical Properties

Molecular FormulaC5H8N4S2
Molecular Weight188.27 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1984
Nitrogen Atoms4
Sulfur Atoms2

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