Furosemide Impurity 26 CAS CATO-C4X-140226
| CAS No. | CATO-C4X-140226 |
| Molecular Formula | C7H3Cl3O4S |
| Molecular Weight | 289.52 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 289.52 g/mol gives Furosemide Impurity 26 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Furosemide Impurity 26 (CAS CATO-C4X-140226), a pharmacopoeial impurity reference standard (molecular formula C7H3Cl3O4S, MW 289.52 g/mol) used for the identification and quantification of trace impurities in APIs.
Furosemide Impurity 26 (C7H3Cl3O4S) contains a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H3Cl3O4S |
| Molecular Weight | 289.52 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Sulfur Atoms | 1 |
Related Furosemide Standards
- Furosemide Impurity 16 (CAS 3740-18-9)
- Furosemide Impurity 55 (CAS 76852-02-3)
- Furosemide Impurity 50 (CAS CATO-C4X-140250)
- Furosemide Impurity 44 (CAS CATO-C4X-140244)
- Furosemide Impurity 31 (CAS 4818-85-3)
- Furosemide Impurity 45 (CAS CATO-C4X-140245)
- Furosemide Impurity 8 (CAS 41332-59-6)
- Furosemide Impurity 19 (CAS CATO-C4X-140219)
Recommended Standards
- 3,4-Dichloro-5-(chlorosulfonyl)benzoic acid (CAS 151104-67-5)
- N-(2-Chloro-4-methylphenyl) 4-boronobenzamide (CAS 913835-39-9)
- 6-Bromo-4-chloro-2-ethyl-8-fluoroquinazoline (CAS 1602524-43-5)
- Boronic acid, b-[3-[[[(3-chlorophenyl)methyl]amino]carbonyl]phenyl]- (CAS 874288-26-3)
- Cinitapride impurity 6 (CAS CATO-C4X-29086)
- Testosterone Impurity 35 (CAS CATO-C4X-243235)
- Lamivudine EP Impurity H (CAS 160552-54-5)
- 2-(Aminomethyl)benzo[d]oxazole-5-carbonyl chloride (CAS 1806532-66-0)
- 7-Methoxy-1-methyl-1H-indole (CAS 51460-41-4)
- 2-(Chloromethyl)-8-methoxyquinoline (CAS 1351516-38-5)
- H-trans-DL-β-Pro-4-(2-pyridinyl)-OH·2HCl (CAS 1049739-70-9)
- 5-(Aminomethyl)-1,2,4-oxadiazole-3-carboxamide (CAS 893752-05-1)
- Ethyl 1-(5-(methylamino)pyridin-2-yl)-1H-pyrazole-4-carboxylate (CAS 1624261-04-6)
- Peptide Impurity 40 (CAS CATO-CPTD788840)
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