Metoclopramide Impurity 133 HCl CAS CATO-C4X-1415133
| CAS No. | CATO-C4X-1415133 |
| Molecular Formula | C14H21Cl2N3O2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C14H21Cl2N3O2HCl, Metoclopramide Impurity 133 HCl contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 370.70 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a process- or degradation-related impurity, Metoclopramide Impurity 133 HCl (CAS CATO-C4X-1415133, C14H21Cl2N3O2HCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Metoclopramide Impurity 133 HCl under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H21Cl2N3O2 HCl |
| Molecular Weight | 370.70 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Metoclopramide Standards
- Metoclopramide EP Impurity E (CAS 100-36-7)
- Metoclopramide Impurity 68 (CAS 101385-94-8)
- Metoclopramide impurity 70 (CAS 102313-35-9)
- Metoclopramide Impurity 11 (CAS 111049-74-2)
- Metoclopramide-related Impurity (CAS 121048-67-7)
- Metoclopramide-d3 (CAS 1216522-89-2)
- Metoclopramide impurity 60 (CAS 1242047-97-7)
- Metoclopramide Impurity 83 (CAS 1242047-99-9)
Recommended Standards
- Rosuvastatin Impurity 34 (CAS CATO-C4X-116934)
- Tenofovir Impurity 74 (CAS 1796539-83-7 (free base))
- Dapagliflozin Impurity N34 (CAS 1443341-94-3)
- (S)-2-((tert-Butoxycarbonyl)amino)-3-((1-methyl-1H-benzo[d]imidazol-2-yl)amino)propanoic acid (CAS 1956437-62-9)
- 1187163-55-8 Ethyl 5-(3-methylpyridin-2-yl)thiophene-2-carboxylate MFCD13152503 (CAS 1187163-55-8)
- 5-Ethyl-2,2-dimethyl-1,3-dioxane-4,6-dione (CAS 17216-65-8)
- 2-(4-Vinylphenyl)ethanol (CAS 45966-73-2)
- Ethyl 2-propionamido-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate (CAS 62159-42-6)
- 1-(oxolan-3-yl)propan-2-amine (CAS 910389-29-6)
- Semaglutide impurity 29 (CAS 110990-08-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com