Loratadine Impurity 80 CAS CATO-C4X-142680
| CAS No. | CATO-C4X-142680 |
| Molecular Formula | C26H27N3 |
| Molecular Weight | 381.51 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Loratadine Impurity 80 (CAS CATO-C4X-142680), a pharmacopoeial impurity reference standard (molecular formula C26H27N3, MW 381.51 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Loratadine Impurity 80 (C26H27N3) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO manufactures Loratadine Impurity 80 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C26H27N3 |
| Molecular Weight | 381.51 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 3 |
Related Loratadine Standards
- Loratadine Impurity 16 (CAS CATO-C4X-142616)
- Loratadine Impurity 17 (CAS 133330-56-0)
- Loratadine Impurity 28 (CAS CATO-C4X-142628)
- Loratadine Impurity 88 (CAS CATO-C4X-142688)
- Loratadine (CAS 79794-75-5)
- Loratadine EP Impurity E (CAS 170727-59-0)
- Loratadine EP Impurity 41 (CAS 169253-13-8)
- Loratadine Impurity 5 (CAS 167891-69-2)
Recommended Standards
- Lercanidipine Impurity 60 (CAS 100427-51-8)
- Venlafaxine Impurity 70 (CAS CATO-C4X-143470)
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- Dutaverine Impurity 30 (CAS CATO-C4X-243530)
- Evocalcet Impurity 71 (CAS CATO-C4X-248571)
- Mirabegron EP Impurity B (CAS 391901-45-4)
- Tetrabenazine Impurity 25-D9 (CAS CATO-C4X-274825)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com