Betamethasone impurity 101 CAS CATO-C4X-1437101
| CAS No. | CATO-C4X-1437101 |
| Molecular Formula | C22H28FO8P |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 493.42 g/mol gives Betamethasone impurity 101 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Betamethasone impurity 101 (CAS CATO-C4X-1437101), a pharmacopoeial impurity reference standard (molecular formula C22H28FO8PNa, MW 493.42 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a flavonoid core, a phosphate ester group, a hydroxyl group, an ether linkage, fluorine substitution, Betamethasone impurity 101 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 493.42 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H28FO8P 2*Na |
| Molecular Weight | 493.42 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
Related Betamethasone Standards
- Betamethasone Cyclic 17,21-(Ethyl Orthopropionate) (CAS 1062-09-5)
- Betamethasone impurity 91 (CAS 114488-14-1)
- Betamethasone impurity 97 (CAS 1150311-95-7)
- Betamethasone Impurity N22 (CAS 116522-68-0)
- Betamethasone Impurity 27 (CAS 116846-77-6)
- Betamethasone impurity 51 (CAS 1184871-61-1)
- Betamethasone Dipropionate EP Impurity G (CAS 1186048-33-8)
- Betamethasone Dipropionate impurity 02 (CAS 1186048-34-9)
Recommended Standards
- Lurasidone Impurity 31 (CAS CATO-C4X-102831)
- N-Nitroso Cinacalcet Impurity 1 (CAS CATO-C4X-105971)
- Topiroxostat impurity 71 (CAS CATO-C4X-105571)
- Trifluridine Impurity 6 (CAS 129664- 48-8)
- (2S,3R)-3-(((S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-5-(tert-butoxy)-5-oxopentanoyl)oxy)-2-((tert-butoxycarbonyl)amino)butanoic acid (CAS 944283-35-6)
- Taurine (CAS 107-35-7)
- (R)-3,3-Dimethylbutane-1,2-diol (CAS 31612-63-2)
- 3-Nitro-5,6,7,8-tetrahydro-1,6-naphthyridine (CAS 123792-68-7)
- (2-Bromo-4,5-dimethoxyphenoxy)trimethylsilane (CAS 2104695-66-9)
- Peptide Impurity 64 (CAS CATO-CPTD788964)
Why CATO?
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