Betamethasone Impurity 112 CAS CATO-C4X-1437112
| CAS No. | CATO-C4X-1437112 |
| Molecular Formula | C24H30O5 |
| Molecular Weight | 398.49 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Betamethasone Impurity 112.
As a process- or degradation-related impurity, Betamethasone Impurity 112 (CAS CATO-C4X-1437112, C24H30O5) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Betamethasone Impurity 112 (C24H30O5) is characterized by a flavonoid core, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Betamethasone Impurity 112 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C24H30O5 |
| Molecular Weight | 398.49 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
Related Betamethasone Standards
- Betamethasone Impurity N1 (CAS 910-99-6)
- Betamethasone Impurity 121 (CAS CATO-C4X-1437121)
- Betamethasone Impurity 122 (CAS CATO-C4X-1437122)
- Betamethasone Impurity 89 (CAS CATO-C4X-143789)
- Betamethasone-d5 (CAS CATO-CCAD301382)
- Betamethasone Impurity 86 (CAS 560-34-9)
- Betamethasone Impurity 136 (CAS CATO-C4X-1437136)
- Betamethasone Impurity 38 (CAS 25121-04-4)
Recommended Standards
- Budesonide Impurity 14 (CAS 5541-37-7)
- Perindopril Impurity 71 (CAS CATO-C4X-125271)
- Perindopril Impurity 106 (CAS CATO-C4X-1252106)
- Eplerenone Impurity 11 (CAS 192704-70-4)
- Midazolam EP Impurity F (CAS 2886-65-9)
- Torasemide Impurity 15 (CAS CATO-C4X-183615)
- N-Nitroso Amoxicillin Impurity 98 (CAS CATO-C4X-114898)
- 2-(1,3-Dioxolan-2-ylmethyl)benzoic acid (CAS 898767-07-2)
- 3-methanesulfinylaniline hydrochloride (CAS 861609-75-8)
- 4’-Bromo-3’-methoxyacetophenone (CAS 50870-44-5)
- 4-((2,6-Dichlorobenzyl)thio)-3-methyl-3H-imidazo[4,5-c]pyridine (CAS 87035-12-9)
- Pralatrexate Impurity 3 (CAS CATO-C4X-22143)
- 13560-90-2 4,5,6,7,13,14,15,16,19,19,20,20-Dodecachloroheptacyclo[9.6.1.1~4,7~.1~13,16~.0~2,10~.0~3,8~.0~12,17~]icosa-5,14-diene (non-preferred name) DTXSID70675901 (CAS 13560-90-2)
- Semaglutide impurity 268 (CAS CATO-C4X-2226268)
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