Betamethasone Impurity 121 CAS CATO-C4X-1437121
| CAS No. | CATO-C4X-1437121 |
| Molecular Formula | C24H30O5 |
| Molecular Weight | 398.49 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Betamethasone Impurity 121 is closely related to a flavonoid core, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Betamethasone Impurity 121 (CAS CATO-C4X-1437121, C24H30O5) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Betamethasone Impurity 121 (C24H30O5) contains a flavonoid core, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 398.49 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C24H30O5 |
| Molecular Weight | 398.49 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
Related Betamethasone Standards
- Betamethasone Impurity N1 (CAS 910-99-6)
- Betamethasone Impurity 112 (CAS CATO-C4X-1437112)
- Betamethasone Impurity 122 (CAS CATO-C4X-1437122)
- Betamethasone Impurity 89 (CAS CATO-C4X-143789)
- Betamethasone-d5 (CAS CATO-CCAD301382)
- Betamethasone Impurity 86 (CAS 560-34-9)
- Betamethasone Impurity 136 (CAS CATO-C4X-1437136)
- Betamethasone Impurity 38 (CAS 25121-04-4)
Recommended Standards
- Budesonide Impurity 14 (CAS 5541-37-7)
- Eplerenone Impurity 11 (CAS 192704-70-4)
- Perindopril Impurity 71 (CAS CATO-C4X-125271)
- Eplerenone EP Impurity C (CAS 95716-70-4)
- Flurbiprofen Impurity 65 (CAS CATO-C4X-144465)
- Benzocaine EP Impurity C (CAS 582-33-2)
- Nintedanib Impurity 159 (CAS CATO-C4X-1814159)
- Prilocaine impurity 36 (CAS CATO-C4X-193436)
- 3-(3-Methyl-7-oxo-7H-thiazolo[3,2-b][1,2,4]triazin-6-yl)propanoic acid (CAS 16943-35-4)
- Gilvocarcin M (CAS 77879-89-1)
- 2-(2-Furoyl)-1,2,3,4-tetrahydroisoquinolin-7-amine (CAS 1018509-55-1)
- Methyl (2S,4S)-4-fluoro-2-methylpyrrolidine-2-carboxylate (CAS 2227198-74-3)
- 2,5-Bis(3-bromophenyl)-1,3,4-oxadiazole (CAS 84832-73-5)
- Met(O)14-Exenatide trifluoroacetate salt (CAS 1678417-38-3)
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