Betamethasone impurity 94 CAS CATO-C4X-143794
| CAS No. | CATO-C4X-143794 |
| Molecular Formula | C22H28FO8P |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Betamethasone impurity 94 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
As a process- or degradation-related impurity, Betamethasone impurity 94 (CAS CATO-C4X-143794, C22H28FO8PNa) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Betamethasone impurity 94 (C22H28FO8PNa) is characterized by a flavonoid core, a phosphate ester group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C22H28FO8P 2*Na |
| Molecular Weight | 493.42 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
Related Betamethasone Standards
- Betamethasone Cyclic 17,21-(Ethyl Orthopropionate) (CAS 1062-09-5)
- Betamethasone impurity 91 (CAS 114488-14-1)
- Betamethasone impurity 97 (CAS 1150311-95-7)
- Betamethasone Impurity N22 (CAS 116522-68-0)
- Betamethasone Impurity 27 (CAS 116846-77-6)
- Betamethasone impurity 51 (CAS 1184871-61-1)
- Betamethasone Dipropionate EP Impurity G (CAS 1186048-33-8)
- Betamethasone Dipropionate impurity 02 (CAS 1186048-34-9)
Recommended Standards
- Sitagliptin Intermediates Impurity (CAS 762240-92-6)
- Montelukast Impurity N6 (CAS 66-40-0)
- Tizanidine Impurity 51 (CAS CATO-C4X-144551)
- 3-Bromo-2-methoxyisonicotinic acid (CAS 1211586-89-8)
- 285978-19-0 N-[2,5-Dioxo(4-~13~C,3-~15~N)imidazolidin-4-yl]urea DTXSID20745769 (CAS 285978-19-0)
- tert-Butyl N-(2-hydroxycyclohexyl)-N-methylcarbamate (CAS 561307-37-7)
- 5-methylthieno[2,3-d]pyrimidine-4-carboxylic acid (CAS 1215494-47-5)
- 1-(3,4,5-Trifluorophenyl)but-3-en-1-ol (CAS 801318-20-7)
- (+)-Medicarpin (CAS 33983-39-0)
- Des-Ser32-Tirzepatide (CAS CATO-CPTD788942)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com