Halometasone impurity 16 CAS CATO-C4X-144616
| CAS No. | CATO-C4X-144616 |
| Molecular Formula | C22H27Cl3F2O5 |
| Molecular Weight | 515.80 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C22H27Cl3F2O5, Halometasone impurity 16 contains a flavonoid core, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 515.80 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies Halometasone impurity 16 (CAS CATO-C4X-144616), a pharmacopoeial impurity reference standard (molecular formula C22H27Cl3F2O5, MW 515.80 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H27Cl3F2O5 |
| Molecular Weight | 515.80 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/Cl-containing |
Related Halometasone Standards
- Halometasone impurity 11 (CAS CATO-C4X-144611)
- Halometasone Impurity 1 (CAS 23961-24-2)
- Halometasone Impurity N3 (CAS 23961-22-0)
- Halometasone Impurity 2 (CAS CATO-C4X-14462)
- Halometasone Impurity 8 (CAS 28895-70-7)
- Halometasone impurity 12 (CAS CATO-C4X-144612)
- Halometasone impurity 10 (CAS CATO-C4X-144610)
- Halometasone impurity 13 (CAS CATO-C4X-144613)
Recommended Standards
- 3-Hydroxy-2,4,6-triiodobenzoic Acid (CAS 53279-72-4)
- 1,4-Bis(bromomethyl)-2,5-diiodobenzene (CAS 56403-29-3)
- 6-Methoxy-2,2’,4,4’-tetrabromodiphenyl ether (CAS 102739-99-1)
- Dodecanoic acid, 12-[[5-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]amino]-, 2,3-dihydroxypropyl ester (CAS 799812-64-9)
- Cefotaxime Impurity 98 (CAS CATO-C4X-120198)
- Lidocaine Impurity 75 (CAS CATO-C4X-167975)
- Nafamostat Impurity 63 (CAS 121714-82-7)
- 4-(4-Ethyl-5-((2-methylbenzyl)thio)-4H-1,2,4-triazol-3-yl)pyridine (CAS 677721-22-1)
- 5-Bromo-2-mercaptobenzoic acid (CAS 61954-80-1)
- Nadolol (CAS 42200-33-9)
- (2-Methoxybenzyl)(4-methylbenzyl)amine (CAS 353777-77-2)
- Benzo[d]cyclopenta[4,5]pyrrolo[1,2-a]imidazole (CAS 161853-14-1)
- Methyl 2-bromo-5-(trifluoromethyl)isonicotinate (CAS 1227594-30-0)
- His-Cyclic-Semaglutide (CAS CATO-C4X-2226182)
Why CATO?
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