Beclometasone Impurity 35 CAS CATO-C4X-147435
| CAS No. | CATO-C4X-147435 |
| Molecular Formula | C22H27BrO3 |
| Molecular Weight | 419.35 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Beclometasone Impurity 35 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Beclometasone Impurity 35 (CAS CATO-C4X-147435) is a certified pharmaceutical impurity reference standard with the molecular formula C22H27BrO3 and a molecular weight of 419.35 g/mol.
Owing to a steroid core, a hydroxyl group, an ether linkage, bromine substitution, Beclometasone Impurity 35 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 419.35 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C22H27BrO3 |
| Molecular Weight | 419.35 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Br-containing |
Related Beclometasone Standards
- Beclometasone Impurity 46 (CAS CATO-C4X-147446)
- Beclometasone Impurity 28 (CAS CATO-C4X-147428)
- Beclometasone Impurity 33 (CAS CATO-C4X-147433)
- Beclometasone Impurity 45 (CAS 34542-51-3)
- Beclometasone Dipropionate Monohydrate EP Impurity U (CAS 79578-39-5)
- Beclometasone Dipropionate Monohydrate EP Impurity V (CAS 205105-83-5)
- Beclometasone Impurity 47 (CAS CATO-C4X-147447)
- Beclometasone Impurity 44 (CAS 18769-20-5)
Recommended Standards
- 4-Amino-5-benzoyl-2-{[(3,4-dichlorophenyl)methyl]sulfanyl}thiophene-3-carbonitrile (CAS 478081-53-7)
- (2R,3S,5R)-5-(2-Fluoro-6-(4-nitrophenethoxy)-9H-purin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol (CAS 132183-39-2)
- 4-Amino-5-benzoyl-2-((2,4-dichlorobenzyl)thio)thiophene-3-carbonitrile (CAS 478081-52-6)
- (2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-phenylmorpholine (CAS 171338-33-3)
- Gadodiamide Impurity 9 (CAS CATO-C4X-31439)
- Sitagliptin Phosphate Monohydrate EP Impurity B (CAS 1345822-87-8)
- Peramivir Impurity 37 (CAS CATO-C4X-183337)
- (2-Methylpyrimidin-5-yl)-acetonitrile (CAS 1581684-23-2)
- (S)-6,8-Dibromochroman-4-amine (CAS 1213943-03-3)
- Nicardipine Hydrochloride (CAS 54527-84-3)
- 2-Methyl-4-(1h-1,2,4-triazol-1-yl)benzoic acid (CAS 220141-17-3)
- 1-(2-Chlorophenyl)-3-(furan-2-yl)-1h-pyrazol-5-amine (CAS 956751-80-7)
- 1-(1-((Benzyloxy)carbonyl)azetidin-3-yl)-1h-1,2,3-triazole-4-carboxylic acid (CAS 1506134-31-1)
- Semaglutide impurity 247 (CAS CATO-C4X-2226247)
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