Midazolam Impurity 32 CAS CATO-C4X-150932
| CAS No. | CATO-C4X-150932 |
| Molecular Formula | C18H12ClFN2O2 |
| Molecular Weight | 342.75 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 342.75 g/mol gives Midazolam Impurity 32 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Midazolam Impurity 32 (CAS CATO-C4X-150932) is a certified pharmaceutical impurity reference standard with the molecular formula C18H12ClFN2O2 and a molecular weight of 342.75 g/mol.
Based on its molecular formula C18H12ClFN2O2, Midazolam Impurity 32 contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 342.75 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Midazolam Impurity 32 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H12ClFN2O2 |
| Molecular Weight | 342.75 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Midazolam Standards
- Midazolam Impurity 1 (CAS 59468-90-5)
- Midazolam EP Impurity D (CAS 59468-83-6)
- Midazolam Impurity 41 (CAS 59468-85-8)
- Midazolam Impurity 33 (CAS CATO-C4X-150933)
- Midazolam EP Impurity I (CAS 112811-67-3)
- Midazolam Impurity 13 (CAS CATO-C4X-150913)
- Midazolam Impurity 25 (CAS CATO-C4X-150925)
- Midazolam-d5 (Major) Discontinued See M343003 (CAS 395067-42-2)
Recommended Standards
- Clozapine Impurity 22 (CAS CATO-C4X-134022)
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- Methyl 3-amino-1-(4-chlorophenyl)-1-cyano-4-fluoro-1H-indene-2-carboxylate (CAS 339029-62-8)
- Ethyl (8-amino-3-(4-chlorophenyl)pyrido[2,3-b]pyrazin-6-yl)carbamate (CAS 28642-75-3)
- Baclofen impurity 31 (CAS CATO-C4X-101231)
- Fluorescein Impurity 6 (CAS 2321-08-6)
- Fezolinetant Impurity 33 (CAS CATO-C4X-327033)
- 2-(3-Chlorophenyl)-2-(1-pyrrolidinyl)ethylamine (CAS 866781-98-8)
- 2-Amino-4-[benzyl(methyl)amino]-6-chloropyrimidine-5-carbaldehyde (CAS 142979-46-2)
- 2-Bromo-3-oxopentane-1,5-diyl bis(dihydrogen phosphate) (CAS 80393-44-8)
- 1-(Pyrimidin-4-yl)prop-2-en-1-ol (CAS 1494723-75-9)
- 3-(1-Phenylethyl)benzo[b]thiophene (CAS 114838-47-0)
- 87314-49-6 3,6-dichlorobenzene-1,2-dithiol DTXSID00404120 (CAS 87314-49-6)
- Liraglutide Impurity 10 TFA Salt (CAS CATO-C4X-199210)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com