Sorafenib EP Impurity A CAS 284462-37-9
| CAS No. | 284462-37-9 |
| Molecular Formula | C13H13N3O2 |
| Molecular Weight | 243.26 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Sorafenib EP Impurity A under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies Sorafenib EP Impurity A (CAS 284462-37-9), a pharmacopoeial impurity reference standard (molecular formula C13H13N3O2, MW 243.26 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C13H13N3O2, Sorafenib EP Impurity A contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 243.26 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C13H13N3O2 |
| Molecular Weight | 243.26 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 3 |
Related Sorafenib Standards
- Sorafenib Impurity 61 (CAS 284462-78-8)
- Sorafenib Impurity 54 (CAS 1153328-25-6)
- Sorafenib Impurity 27 (CAS 757251-59-5)
- Sorafenib Impurity 12 (CAS 343247-69-8)
- Sorafenib Impurity 15 (CAS CATO-C4X-112415)
- Sorafenib impurity 65 (CAS CATO-C4X-112465)
- Sorafenib Impurity 45 (CAS 46843-47-4)
- Sorafenib Impurity 30 (CAS 1012058-77-3)
Recommended Standards
- Agomelatine Impurity 47 (CAS CATO-C4X-110847)
- (1S,4S)-5-(tert-Butoxycarbonyl)-2-oxa-5-azabicyclo[2.2.1]heptane-4-carboxylic acid (CAS 2920198-60-1)
- Eltrombopag Impurity 157 (CAS CATO-C4X-1198157)
- 932334-10-6 4-{[(3-Aminopyridin-2-yl)amino]methyl}benzoic acid MFCD15732379 (CAS 932334-10-6)
- Mirabegron Impurity 63 (CAS 1376625-93-2)
- Tiamulin EP Impurity J (CAS 31771-36-5)
- Piribedil Impurity 18 (CAS CATO-C4X-281318)
- 6-Hydroxy-5-methoxy-2-methylpyrimidin-4(3H)-one (CAS 851985-99-4)
- (S)-2-Amino-5,5,5-trifluoro-4,4-dimethylpentan-1-ol (CAS 2766301-16-8)
- 3-Cyano-3-(2,4-dichlorophenyl)propanoic acid (CAS 1003707-08-1)
- 3,3-dimethoxycyclobutane-1-carbaldehyde (CAS 1031334-86-7)
- N-(4-Bromophenyl)-2-(m-tolyloxy)acetamide (CAS 62095-55-0)
- ABT-348 (CAS 1227939-82-3)
- Anorexigenic Peptide (CAS 69275-10-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com