Clonidine Impurity 7 CAS CATO-C4X-15947
| CAS No. | CATO-C4X-15947 |
| Molecular Formula | C9H8Cl2N4O |
| Molecular Weight | 259.09 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Clonidine Impurity 7 (CAS CATO-C4X-15947), a pharmacopoeial impurity reference standard (molecular formula C9H8Cl2N4O, MW 259.09 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Clonidine Impurity 7 (C9H8Cl2N4O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), Clonidine Impurity 7 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H8Cl2N4O |
| Molecular Weight | 259.09 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Clonidine Standards
Recommended Standards
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- 3-Amino-3-(3-ethoxy-4-isopropoxyphenyl)-propanoic acid 696645-82-6 8323AE C14H21NO4 (CAS 696645-82-6)
- N-(cyclohexylmethyl)-O-methylhydroxylamine (CAS 1549665-47-5)
- 3,4-dichloro-6-methoxy-1,7-naphthyridine (CAS 2074703-17-4)
- rel-(2R,3R,11R,12R)-1,4,7,10,13,16-Hexaoxacyclooctadecane-2,3,11,12-tetracarboxylic acid (CAS 119719-58-3)
- 2-amino-4-methoxy-5-nitrophenol (CAS 1384701-67-0)
- Semaglutide Impurity 140 (CAS CATO-C4X-2226140)
Why CATO?
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