Dasatinib impurity 60 CAS CATO-C4X-160760
| CAS No. | CATO-C4X-160760 |
| Molecular Formula | C18H17ClN4OS |
| Molecular Weight | 372.87 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Dasatinib impurity 60 (C18H17ClN4OS) is characterized by a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Dasatinib impurity 60 (CAS CATO-C4X-160760) is a certified pharmaceutical impurity reference standard with the molecular formula C18H17ClN4OS and a molecular weight of 372.87 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Dasatinib impurity 60 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H17ClN4OS |
| Molecular Weight | 372.87 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Dasatinib Standards
- Dasatinib impurity 67 (CAS 302964-06-3)
- Dasatinib Impurity N57 (CAS 1245157-42-9)
- Dasatinib Impurity 74 (CAS CATO-C4X-160774)
- Dasatinib Impurity 46 (CAS CATO-C4X-160746)
- Dasatinib Impurity 29 (CAS CATO-C4X-160729)
- Dasatinib Dichloro Impurity (CAS 302964-08-5)
- Dasatinib Impurity 55 (CAS CATO-C4X-160755)
- Dasatinib Impurity 14 (CAS 910297-71-1)
Recommended Standards
- Etoricoxib Impurity 10 (CAS 646459-45-2)
- 1,3-Dibromo-2-(3-bromopropoxy)benzene (CAS 206347-33-3)
- N-(2-((2-(4-chlorophenyl)-4-methylthiazol-5-yl)methoxy)phenyl)acetamide (CAS 866018-32-8)
- Bisoprolol Impurity 118 (CAS 2919749-44-1)
- Atrasentan Impurity 48 (CAS 1059052-55-9)
- Trimetazidine Impurity 11 (CAS CATO-C4X-180311)
- Bilastine impurity 112 (CAS CATO-C4X-2253112)
- N-butyl-3-(methylamino)benzene-1-sulfonamide (CAS 1803583-34-7)
- (2-Pyrrolidin-1-ylpropyl)amine (CAS 50998-07-7)
- Di-tert-butyl 2,2'-((2-((2-(tert-butoxy)-2-oxoethyl)(2-(2,2,2-trifluoroacetamido)ethyl)amino)ethyl)azanediyl)diacetate (CAS 180152-84-5)
- Ethyl (2-((3-(furan-2-yl)-1,2,4-oxadiazol-5-yl)methyl)phenyl)carbamate (CAS 1797858-80-0)
- N,N-Bis(2-Chloroethyl)-4-[(4-Fluoro-2-Methylphenyl)Iminomethyl]-3-Methylaniline (CAS 2024-08-0)
- 1-Phenyl-N-[2-(trifluoromethyl)phenyl]cyclopentane-1-carboxamide (CAS 1024186-50-2)
- Semaglutide impurity 59 (CAS CATO-C4X-222659)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com