Dolutegravir Impurity 40 CAS CATO-C4X-162040
| CAS No. | CATO-C4X-162040 |
| Molecular Formula | C20H18F2N3O5 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Dolutegravir Impurity 40.
Dolutegravir Impurity 40 (CAS CATO-C4X-162040) is a high-purity analytical reference standard with the molecular formula C20H18F2N3O5Na and a molecular weight of 441.37 g/mol.
Based on its molecular formula C20H18F2N3O5Na, Dolutegravir Impurity 40 contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 441.37 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Dolutegravir Impurity 40 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H18F2N3O5 Na |
| Molecular Weight | 441.37 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Dolutegravir Standards
- Dolutegravir (CAS 1051375-16-6)
- Dolutegravir Sodium Salt (CAS 1051375-19-9)
- Dolutegravir Impurity 22 (CAS 1206102-11-5)
- Dolutegravir Sodium Monohydrate - API Standards (CAS 1229006-39-6)
- Dolutegravir Impurity N13 (CAS 1246616-73-8)
- Dolutegravir Impurity 14 (CAS 127958-23-0)
- Dolutegravir Impurity 2 (CAS 1309560-49-3)
- Dolutegravir Impurity 27 (CAS 1335210-31-5)
Recommended Standards
- Cyclohexyldiphenylphosphine Oxide (CAS 13689-20-8)
- (4-(Difluoromethyl)benzo[d]oxazol-2-yl)methanol (CAS 1807045-24-4)
- Methyl 5-(Bromomethyl)nicotinate (CAS 877624-38-9)
- 1-(3-Bromo-propyl)-4-octyl-benzene (CAS 1611469-80-7)
- 5-Propyl-2-(pyrrolidin-1-yl)-7-(thiophen-2-yl)thiazolo[4,5-d]pyridazin-4(5H)-one (CAS 1105232-92-5)
- (4-Cyclopropoxy-5-isopropylpyridin-3-yl)methanamine (CAS 1243469-10-4)
- 4-(3-Bromothiophen-2-yl)benzoic acid (CAS 930111-09-4)
- Methyl 5-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylate (CAS 1195796-91-8)
- 2-Methyl-4-(thiomorpholine-4-carbonyl)aniline (CAS 1042776-60-2)
- Insulin Pork(≥27 USP units/mg) (CAS 12584-58-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com