Pazopanib Impurity 64 HCl CAS CATO-C4X-172564
| CAS No. | CATO-C4X-172564 |
| Molecular Formula | C20H21N7O2S |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Pazopanib Impurity 64 HCl.
As a process- or degradation-related impurity, Pazopanib Impurity 64 HCl (CAS CATO-C4X-172564, C20H21N7O2SHCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Pazopanib Impurity 64 HCl (C20H21N7O2SHCl) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Pazopanib Impurity 64 HCl under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C20H21N7O2S HCl |
| Molecular Weight | 459.95 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 7 |
| Sulfur Atoms | 1 |
Related Pazopanib Standards
- Pazopanib Impurity 28 (CAS 1072836-76-0)
- Pazopanib Impurity 18 (CAS 121-03-9)
- Pazopanib-d6 (CAS 1219592-01-4)
- Pazopanib Impurity 5 (CAS 1226499-97-3)
- Pazopanib Impurity 6 (CAS 1226499-98-4)
- Pazopanib Impurity 50 (CAS 1226500-00-0)
- Pazopanib Impurity 42 (CAS 1226500-01-1)
- Pazopanib Impurity 37 (CAS 1226500-02-2)
Recommended Standards
- Tofacitinib Impurity 113 (CAS CATO-C4X-1079113)
- Fluticasone Furoate Impurity 4 (CAS CATO-C4X-32544)
- Calcipotriol Impurity 39 (CAS 7691-76-1)
- Tenofovir alafenamide impurity 84 (CAS 2734880-21-6（free base）)
- Ethyl 2-methyl-2,3-dihydrobenzofuran-5-carboxylate (CAS 100117-42-8)
- 1-((3-Bromophenoxy)methyl)cyclobutanecarboxylic acid (CAS 1387558-82-8)
- 6-O-Methyl-D-glucose (CAS 2461-70-3)
- PBS 57 (CAS 898531-99-2)
- 2-(Chloromethoxy)acetic Acid Ethyl Ester (CAS 124186-08-9)
- Fibrinogen-Binding Inhibitor Peptide (CAS 89105-94-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com