Vancomycin Impurity 20 CAS CATO-C4X-177520

Description

The occurrence of Vancomycin Impurity 20 is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a phosphate ester group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies Vancomycin Impurity 20 (CAS CATO-C4X-177520), a pharmacopoeial impurity reference standard (molecular formula C88H97Cl2N9O24P, MW 1766.64 g/mol) used for the identification and quantification of trace impurities in APIs.

Structurally, Vancomycin Impurity 20 (C88H97Cl2N9O24P) contains a nitrogen-containing heterocyclic scaffold, an amide group, a phosphate ester group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 44.0, corresponding to approximately 44 ring(s) or double-bond equivalent(s). With a molecular weight of 1766.64 g/mol, it falls into the high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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