Amlodipine Besylate EP Impurity F CAS 140171-66-0
| CAS No. | 140171-66-0 |
| Molecular Formula | C19H23ClN2O5 |
| Molecular Weight | 394.85 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Amlodipine Besylate EP Impurity F (CAS 140171-66-0, C19H23ClN2O5) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Amlodipine Besylate EP Impurity F (C19H23ClN2O5) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Amlodipine Besylate EP Impurity F under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H23ClN2O5 |
| Molecular Weight | 394.85 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Amlodipine Standards
- Amlodipine Impurity 38 (CAS 113994-37-9)
- Amlodipine Impurity N21 (CAS 2170111-18-7)
- Amlodipine Impurity N20 (CAS 2170104-02-4)
- Amlodipine Impurity 76 (CAS CATO-C4X-109576)
- Amlodipine Impurity N1 (CAS 194472-27-0)
- Amlodipine Impurity 30 (CAS 496024-43-2)
- Amlodipine Impurity 60 (CAS 949155-13-9)
- Amlodipine Impurity 78 (CAS CATO-C4X-109578)
Recommended Standards
- NLX-101 (CAS 635323-95-4)
- Empagliflozin Impurity N6 (CAS 333359-90-3)
- Benzyl N-({4-[(4-chlorophenyl)carbamoyl]phenyl}methyl)carbamate (CAS 477847-75-9)
- N-{6-[4-(6-Chloro-2-pyridinyl)piperazino]-3,5-dicyano-2-pyridinyl}-N,N-dimethyliminoformamide (CAS 339110-72-4)
- Tafamidis Impurity 9 (CAS 1395964-06-3)
- Lesinurad Impurity 2 (CAS 1384208-36-9)
- Docetaxel Impurity 69 (CAS 155396-69-3)
- 2-Chloro-5-[(4-fluorophenyl)sulfamoyl]benzoic acid (CAS 313225-61-5)
- Methyl 1-(2-(4-chloro-3-methylphenoxy)acetyl)-1H-indole-3-carboxylate (CAS 429627-08-7)
- 4-Phenoxy-1,1'-biphenyl (CAS 3933-94-6)
- Methyl 3-chloro-5-fluoro-4-methoxybenzoate (CAS 1520844-29-4)
- 9-(2-(Dibenzylamino)ethyl)-6-methyl-2,3,4,9-tetrahydro-1H-carbazol-1-one (CAS 300801-39-2)
- 5-Bromo-3-(chloromethyl)-6-(difluoromethyl)pyridin-2-amine (CAS 1804694-25-4)
- Glu17-Semaglutide (CAS CATO-C4X-2226209)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com