Bendamustine Impurity 31 CAS CATO-C4X-127131
| CAS No. | CATO-C4X-127131 |
| Molecular Formula | C19H27Cl2N3O3S |
| Molecular Weight | 448.41 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 448.41 g/mol gives Bendamustine Impurity 31 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Bendamustine Impurity 31 (CAS CATO-C4X-127131, C19H27Cl2N3O3S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Bendamustine Impurity 31 (C19H27Cl2N3O3S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 448.41 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Bendamustine Impurity 31 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H27Cl2N3O3S |
| Molecular Weight | 448.41 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Bendamustine Standards
- Bendamustine Impurity 18 (CAS CATO-C4X-127118)
- Bendamustine Impurity 19 (CAS CATO-C4X-127119)
- Bendamustine Impurity 20 (CAS CATO-C4X-127120)
- Bendamustine impurity 32 (CAS CATO-C4X-127132)
- Bendamustine USP Related Compound I (CAS 87475-54-5)
- Bendamustine Impurity 14 (CAS CATO-C4X-127114)
- Bendamustine Impurity 15 (CAS CATO-C4X-127115)
- Bendamustine impurity 43 (CAS CATO-C4X-127143)
Recommended Standards
- Tenofovir alafenamide Impurity 16 Free base (CAS CATO-C4X-179769)
- tert-Butyl ((1S,2S)-2-((2,6-dimethoxyphenyl)selanyl)-2,3-dihydro-1H-inden-1-yl)carbamate (CAS 2088566-91-8)
- Tenofovir alafenamide impurity 73 (CAS CATO-C4X-179773)
- Quinacillin (CAS 76788-82-4)
- Carbazochrome Impurity 19 (CAS CATO-C4X-229119)
- Droperidol Impurity 17 (CAS 466118-73-0)
- Agomelatine Impurity 16 (CAS 6836-19-7)
- Cyclopropyl(4-methoxy-3-methylphenyl)methanone (CAS 189347-51-1)
- 3,4-Dichlorofuran-2-carbohydrazide (CAS 1403566-20-0)
- Boc-Ala-OSu (CAS 3392-05-0)
- 2-(4,6-Di-tert-butylpyrimidin-2-yl)ethan-1-amine (CAS 944905-04-8)
- (S)-3-Amino-3-(3-hydroxyphenyl)propanoic acid (CAS 695149-42-9)
- 2,3,5-Trimethyl-2,3-dihydropyrimidin-4(1H)-one (CAS 5821-28-3)
- (Met(O)2?)-Glucagon (1-29) (human, rat, porcine) (CAS 75217-63-9)
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