Tenofovir Alafenamide Impurity 50 CAS 1878175-77-9

Description

The occurrence of Tenofovir Alafenamide Impurity 50 is closely related to a flavonoid core, an amide group, a phosphate ester group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies Tenofovir Alafenamide Impurity 50 (CAS 1878175-77-9), a pharmacopoeial impurity reference standard (molecular formula C17H23N10O4P, MW 462.40 g/mol) used for the identification and quantification of trace impurities in APIs.

The molecular framework of Tenofovir Alafenamide Impurity 50 (C17H23N10O4P) is characterized by a flavonoid core, an amide group, a phosphate ester group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

CATO manufactures Tenofovir Alafenamide Impurity 50 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

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