Nintedanib Impurity 121 CAS CATO-C4X-1814121
| CAS No. | CATO-C4X-1814121 |
| Molecular Formula | C18H15NO4 |
| Molecular Weight | 309.32 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Nintedanib Impurity 121 (CAS CATO-C4X-1814121, C18H15NO4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Nintedanib Impurity 121 (C18H15NO4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. The carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Nintedanib Impurity 121 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H15NO4 |
| Molecular Weight | 309.32 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 1 |
Related Nintedanib Standards
- Nintedanib Impurity 120 (CAS CATO-C4X-1814120)
- Nintedanib Impurity 14 (CAS 1168150-46-6)
- Nintedanib Impurity 53 (CAS 1160293-22-0)
- Nintedanib Impurity 55 (CAS 1438271-13-6)
- Nintedanib Impurity 36 (CAS 1160293-27-5)
- Nintedanib impurity 79 (CAS 2490403-92-2)
- Nintedanib Impurity 186 (CAS CATO-C4X-1814186)
- Nintedanib Impurity 122 (CAS CATO-C4X-1814122)
Recommended Standards
- Indobufen impurity 76 (CAS CATO-C4X-179276)
- Indobufen Impurity 71 (CAS CATO-C4X-179271)
- Indobufen Impurity 10 (CAS 94232-67-4)
- Roxadustat Impurity 39 (CAS CATO-C4X-221339)
- Irbesartan Impurity 41 (CAS CATO-C4X-166641)
- Bilastine Impurity 76 (CAS CATO-C4X-225376)
- Tolvaptan Impurity 38 (CAS 3951-89-1)
- 3-Bromoimidazo[1,2-a]pyrimidine-2-carbonitrile (CAS 1823930-43-3)
- 1,2-Dimyristoyl-rac-glycerol (CAS 20255-94-1)
- 2-[(1-methyl-1h-pyrazol-5-yl)methoxy]acetic acid (CAS 1173076-45-3)
- 1-Ethyl-3-(methoxymethyl)-1,4,5,6,7,8-hexahydropyrazolo[3,4-b]azepine (CAS 583811-73-8)
- Methyl 1-methylphosphinane-4-carboxylate 1-oxide (CAS 2713862-42-9)
- Dimethyl 2,5-dihydrothiophene-3,4-dicarboxylate (CAS 20946-32-1)
- Liraglutide (CAS 204656-20-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com