Nintedanib Impurity 149 CAS CATO-C4X-1814149
| CAS No. | CATO-C4X-1814149 |
| Molecular Formula | C10H10Cl4O3 |
| Molecular Weight | 320.00 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 320.00 g/mol gives Nintedanib Impurity 149 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Nintedanib Impurity 149 (CAS CATO-C4X-1814149), a pharmacopoeial impurity reference standard (molecular formula C10H10Cl4O3, MW 320.00 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C10H10Cl4O3, Nintedanib Impurity 149 contains a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 320.00 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Nintedanib Impurity 149 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H10Cl4O3 |
| Molecular Weight | 320.00 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | ≥95% |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
Related Nintedanib Standards
- Nintedanib Impurity 146 (CAS CATO-C4X-1814146)
- Nintedanib Impurity 147 (CAS CATO-C4X-1814147)
- Nintedanib Impurity 129 (CAS CATO-C4X-1814129)
- Nintedanib Impurity 85 (CAS CATO-C4X-181485)
- Nintedanib Impurity 122 (CAS CATO-C4X-1814122)
- Nintedanib Impurity 89 (CAS CATO-C4X-181489)
- Nintedanib Impurity 154 (CAS CATO-C4X-1814154)
- Nintedanib Impurity 158 (CAS 1023942-14-4)
Recommended Standards
- 3,3′,4,4′-Tetrachloroazobenzene (CAS 14047-09-7)
- 4-Bromo-6-(difluoromethyl)-5-(trifluoromethyl)nicotinic acid (CAS 1804465-12-0)
- Bis(3,5-dichlorophenyl)methanone (CAS 92758-86-6)
- 4-Bromo-5-(difluoromethyl)-2-(trifluoromethyl)nicotinic acid (CAS 1804465-31-3)
- Fenofibrate Impurity 19 (CAS CATO-C4X-164319)
- Empagliflozin Impurity 126 (CAS CATO-C4X-1065126)
- Ledipasvir Impurity 9 (CAS CATO-C4X-33139)
- Mesalazine Impurity 55 (CAS CATO-C4X-132455)
- N-nitroso-N-(4-sulfamoylphenyl)acetamide (CAS CATO-C4X-24931)
- 3-(6-Ethyl-4-oxoquinolin-1(4H)-yl)propanenitrile (CAS 1279218-88-0)
- 4-Iodo-N,N-dimethylbenzamide (CAS 24167-53-1)
- Ethyl 1-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-4-cyano-1H-pyrazole-5-carboxylate (CAS 321574-30-5)
- 1,1'-[(1S)-6,6'-Dimethoxy[1,1'-biphenyl]-2,2'-diyl]bis[1,1-dicyclohexylphosphine] (CAS 246223-35-8)
- Erythropoietin Mimetic Peptide Sequence 20 (CAS 203397-62-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com