Nintedanib Impurity 162 CAS CATO-C4X-1814162
| CAS No. | CATO-C4X-1814162 |
| Molecular Formula | C19H32N6O |
| Molecular Weight | 360.50 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
As a process- or degradation-related impurity, Nintedanib Impurity 162 (CAS CATO-C4X-1814162, C19H32N6O) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, Nintedanib Impurity 162 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 360.50 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C19H32N6O |
| Molecular Weight | 360.50 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 6 |
Related Nintedanib Standards
- Nintedanib Impurity 26 (CAS CATO-C4X-181426)
- Nintedanib Impurity 51 (Z-Isomer) (CAS 2102162-79-6)
- Nintedanib Impurity 34 (CAS 1235004-99-5)
- Nintedanib Impurity 24 (CAS CATO-C4X-181424)
- Nintedanib Impurity 188 (CAS 2676997-47-8)
- Nintedanib Impurity 148 (CAS CATO-C4X-1814148)
- Nintedanib Impurity 13 (CAS 1253769-13-9)
- Nintedanib Impurity 49 (CAS 1168152-07-5)
Recommended Standards
- N-(1-Cyano-1-cyclopropylethyl)-2-((2,5,6-trimethylthieno[2,3-d]pyrimidin-4-yl)thio)acetamide (CAS 849057-27-8)
- Abemaciclib Impurity 163 (CAS CATO-C4X-2937163)
- 5-(1-(Ethylsulfonyl)piperidin-3-yl)-4-((tetrahydrofuran-2-yl)methyl)-4H-1,2,4-triazole-3-thiol (CAS 932918-86-0)
- 1-(1-(4-Chlorophenyl)-2-methylpropan-2-yl)urea (CAS 15240-59-2)
- Flurbiprofen Impurity 173 (CAS CATO-C4X-1444173)
- Arotinolol impurity 27 (CAS CATO-C4X-185427)
- Rapamycin Impurity 7 (CAS CATO-C4X-17467)
- Avatrombopag Impurity 127 (CAS CATO-C4X-2234127)
- 7-(6-Amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-2-yl)hept-6-ynenitrile (CAS 403731-18-0)
- 3,5-Diethoxyisonicotinaldehyde (CAS 164077-50-3)
- 6-(4-Methylpiperazin-1-yl)indoline (CAS 209482-07-5)
- 2-Isopropyl-5-methylthiophen-3-amine (CAS 1521891-99-5)
- 910537-24-5 ht-2 toxin 13c2,d3 (CAS 910537-24-5)
- Tau Peptide (268-282) trifluoroacetate salt (CAS 330456-37-6)
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