Cobicistat Impurity 1 CAS CATO-C4X-18161

Description

Compared with other compounds in its class, the molecular weight of 304.86 g/mol gives Cobicistat Impurity 1 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies Cobicistat Impurity 1 (CAS CATO-C4X-18161), a pharmacopoeial impurity reference standard (molecular formula C18H24N2HCl, MW 304.86 g/mol) used for the identification and quantification of trace impurities in APIs.

The molecular framework of Cobicistat Impurity 1 (C18H24N2HCl) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

As a certified reference material (CRM), Cobicistat Impurity 1 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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