Tolvaptan Impurity 65 CAS CATO-C4X-195565
| CAS No. | CATO-C4X-195565 |
| Molecular Formula | C26H25ClN2O4 |
| Molecular Weight | 464.94 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Tolvaptan Impurity 65 (CAS CATO-C4X-195565, C26H25ClN2O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Tolvaptan Impurity 65 (C26H25ClN2O4) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 15.0, corresponding to approximately 15 ring(s) or double-bond equivalent(s). With a molecular weight of 464.94 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Tolvaptan Impurity 65 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C26H25ClN2O4 |
| Molecular Weight | 464.94 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Tolvaptan Standards
- Tolvaptan Impurity 47 (CAS 150683-52-6)
- Tolvaptan Impurity 96 (CAS 1587638-01-4)
- Tolvaptan Impurity 51 (CAS CATO-C4X-195551)
- Tolvaptan Impurity 116 (CAS 1580889-35-5)
- Tolvaptan Impurity 126 (CAS CATO-C4X-1955126)
- Tolvaptan Impurity 46 (CAS 2468638-31-3)
- Tolvaptan-d7 (CAS 1246818-18-7)
- Tolvaptan Impurity 108 (CAS CATO-C4X-1955108)
Recommended Standards
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- Bexagliflozin Impurity 11 (CAS CATO-C4X-332211)
- Lodoxamide impurity 22 (CAS CATO-C4X-294922)
- Progesterone Impurity 86 (CAS 143955-73-1)
- Mirogabalin Impurity 112 (CAS CATO-C4X-2924112)
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- Methyl 4-bromo-5-iodothiophene-3-carboxylate (CAS 24647-84-5)
- Des-Ile27-Tirzepatide (CAS CATO-CPTD788946)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com