Varenicline Impurity 36 CAS CATO-C4X-196237
| CAS No. | CATO-C4X-196237 |
| Molecular Formula | C11H10N4O5 |
| Molecular Weight | 278.22 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 278.22 g/mol gives Varenicline Impurity 36 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Varenicline Impurity 36 (CAS CATO-C4X-196237), a pharmacopoeial impurity reference standard (molecular formula C11H10N4O5, MW 278.22 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Varenicline Impurity 36 (C11H10N4O5) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 278.22 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Varenicline Impurity 36 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H10N4O5 |
| Molecular Weight | 278.22 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 4 |
Related Varenicline Standards
- Varenicline Impurity 12 (CAS CATO-C4X-196212)
- Varenicline Impurity 40 (CAS CATO-C4X-196240)
- Varenicline Impurity 19 (CAS 230615-69-7)
- Varenicline Impurity 34 (CAS CATO-C4X-196234)
- Varenicline Impurity 47 (CAS CATO-C4X-196247)
- Varenicline Impurity 26 (CAS CATO-C4X-196226)
- Varenicline Impurity 53 (CAS CATO-C4X-196253)
- Varenicline Impurity 52 (CAS CATO-C4X-196252)
Recommended Standards
- Diazolidinylurea (CAS 78491-02-8)
- Entacapone EP Impurity B (CAS 1215039-66-9)
- Succinimidyl-p-nitrophenylacetate (CAS 68123-33-1)
- Tert-butyl (4,4,5,5,5-pentafluoropentyl) carbonate (CAS 1980038-99-0)
- Chlorhexidine Impurity 36 (CAS CATO-C4X-225636)
- Methoxyphenamine Impurity 4 (CAS CATO-C4X-23974)
- Indometacin EP Impurity D (CAS CATO-C4X-147012)
- (4-Oxo-4H-thieno[2,3-d]pyrimidin-3-yl)-acetic acid 18740-34-6 6298AD C8H6N2O3S (CAS 18740-34-6)
- trans-1-chloro-2-acetÂamido cycloÂhexane (CAS 24281-07-0)
- 3-iodo-1h-indole-7-carboxylic acid (CAS 1360953-77-0)
- (Z)-2-Chloro-2-phenylethenesulfonamide (CAS 64984-30-1)
- N-(4-chlorophenyl)-4-methoxybenzenesulfonamide (CAS 97026-74-9)
- 4-Fluoro-3-nitro-1H-pyrrolo[2,3-b]pyridine (CAS 1172067-55-8)
- [Formaldehyde Schiff-base]-Semaglutide Impurity 136 X TFA Salt (CAS CATO-C4X-2226136)
Why CATO?
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