Varenicline Impurity 47 CAS CATO-C4X-196247
| CAS No. | CATO-C4X-196247 |
| Molecular Formula | C13H14F3N3O |
| Molecular Weight | 285.26 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Varenicline Impurity 47 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies Varenicline Impurity 47 (CAS CATO-C4X-196247), a pharmacopoeial impurity reference standard (molecular formula C13H14F3N3O, MW 285.26 g/mol) used for the identification and quantification of trace impurities in APIs.
Varenicline Impurity 47 (C13H14F3N3O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C13H14F3N3O |
| Molecular Weight | 285.26 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Varenicline Standards
- Varenicline Impurity 19 (CAS 230615-69-7)
- Varenicline Impurity 34 (CAS CATO-C4X-196234)
- Varenicline Impurity 40 (CAS CATO-C4X-196240)
- Varenicline Impurity 12 (CAS CATO-C4X-196212)
- Varenicline Impurity 36 (CAS CATO-C4X-196237)
- Varenicline Impurity 52 (CAS CATO-C4X-196252)
- Varenicline Impurity N22 (CAS 2759288-58-7)
- Varenicline Impurity 1 (CAS 230615-53-9)
Recommended Standards
- Carbazochrome impurity 44 (CAS CATO-C4X-229144)
- Adenosine Impurity 3 (CAS CATO-C4X-24193)
- Ganciclovir EP Impurity D (CAS CATO-C4X-10214)
- Adenosine Impurity 4 (CAS CATO-C4X-24194)
- Topiramate Impurity 35 (CAS CATO-C4X-176835)
- Nabumetone Impurity 12 (CAS 2740579-68-2)
- Nemonoxacin Impurity 81 (CAS CATO-C4X-312881)
- N-(3-(N-(Furan-2-ylmethyl)sulfamoyl)phenyl)-4-methoxybenzamide (CAS 522625-85-0)
- Benzyl (2R,4R)-4-methylpiperidine-2-carboxylate (CAS 339183-94-7)
- (S)-1-(1-(Pyridin-4-yl)-1H-benzo[d]imidazol-2-yl)ethanamine (CAS 1398507-92-0)
- 6-Methyl-1H-pyrrolo[3,2-c]pyridine-3-carbaldehyde (CAS 1000342-16-4)
- Ilaprazole Impurity 135 (CAS 125131-90-0)
- (2E)-3-(2-{acetyl[3-(trifluoromethyl)phenyl]amino}-1,3-thiazol-4-yl)acrylic acid (CAS 790272-39-8)
- Liraglutide(14-22)TFA Salt (CAS CATO-C4X-199212)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com