Nebivolol Impurity 59 CAS CATO-C4X-196859
| CAS No. | CATO-C4X-196859 |
| Molecular Formula | 2*C22H27NO4 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C22H27NO4, Nebivolol Impurity 59 contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 369.46 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies Nebivolol Impurity 59 (CAS CATO-C4X-196859), a pharmacopoeial impurity reference standard (molecular formula C22H27NO4, MW 369.46 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Nebivolol Impurity 59 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | 2*C22H27NO4 |
| Molecular Weight | 369.46 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 1 |
Related Nebivolol Standards
- Nebivolol Impurity 66 (CAS 1017878-67-9)
- Nebivolol Impurity 15 (CAS 1029684-20-5)
- Nebivolol Impurity 20 (CAS 105300-40-1)
- Nebivolol Impurity 28 (CAS 112068-01-6)
- D-Nebivolol (SR,RR) (CAS 118457-15-1)
- L-Nebivolol (RS,SS) (CAS 118457-16-2)
- Nebivolol Hydrochloride EP Impurity B (CAS 119365-23-0)
- Nebivolol Impurity 32（SS,RS）or（SR,SS） (CAS 119365-25-2)
Recommended Standards
- Avibactam Impurity 156 DiHCl (CAS CATO-C4X-1348156)
- Lifitegrast Impurity 112 (CAS CATO-C4X-2409112)
- Pomalidomide Impurity 28 (CAS CATO-C4X-135428)
- (5-Bromo-2,3-difluorophenyl)methanamine (CAS 887585-92-4)
- Rebamipide impurity 23 (CAS CATO-C4X-152323)
- 6-((5-Cyanopyrazin-2-yl)amino)-4-((1-methylpiperidin-4-yl)amino)nicotinic acid (CAS 1137477-38-3)
- 6-(2-Methoxyethoxy)-4-methylpyridin-3-amine (CAS 1544844-77-0)
- 3-(5-(Phenylcarbamoyl)-1,3,4-thiadiazol-2-yl)propanoic acid (CAS 1142209-41-3)
- N-(3,4-Dimethoxyphenyl)-2-((4-ethyl-5-(pyridin-2-yl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 578734-69-7)
- Des-Ile27-Tirzepatide (CAS CATO-CPTD788946)
Why CATO?
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