Neostigmine impurity 45 CAS CATO-C4X-204245
| CAS No. | CATO-C4X-204245 |
| Molecular Formula | C25H38N4O4 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Neostigmine impurity 45 (CAS CATO-C4X-204245) is a certified pharmaceutical impurity reference standard with the molecular formula C25H38N4O4CH3O4S and a molecular weight of 569.69 g/mol.
The molecular framework of Neostigmine impurity 45 (C25H38N4O4CH3O4S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C25H38N4O4 2*CH3O4S |
| Molecular Weight | 569.69 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Neostigmine Standards
- Neostigmine Bromide (CAS 114-80-7)
- Neostigmine bromide Impurity 14 (CAS 14318-66-2)
- Neostigmine Impurity 24 (CAS 15799-79-8)
- Neostigmine EP Impurity C (CAS 16088-19-0)
- Neostigmine Methyl Sulfate - Impurity A (Bromide Salt) (CAS 1620-19-5)
- Neostigmine Impurity 50 (CAS 16460-28-9)
- Neostigmine Impurity 4 (CAS 19962-04-0)
- Neostigmine impurity 31 (CAS 22237-93-0（free base）)
Recommended Standards
- Pitavastatin Impurity 125 (CAS 1422058-52-3(free base))
- Omarigliptin Impurity 5 (CAS 1456616-44-6)
- Ibuprofen Impurity 66 (CAS CATO-C4X-108266)
- Pogostol (CAS 21698-41-9)
- rac-cis-3-Amino-1-indanol (CAS 403672-03-7)
- 2-[Amino-(2-chloro-phenyl)-methylene]-malononitrile (CAS 1311280-34-8)
- 6-(4-Ethoxyphenyl)pyridazine-3-thiol (CAS 1225715-79-6)
- 4-chloro-1-isobutyl-1h-pyraZole (CAS 1204901-78-9)
- 4,15-Dioxo-5,8,11,14-tetraoxaoctadecane-1,18-dioic acid (CAS 62538-60-7)
- Neuropeptide SF (human) (CAS 192387-39-6)
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