Osimertinib Impurity 104 CAS CATO-C4X-2045104
| CAS No. | CATO-C4X-2045104 |
| Molecular Formula | C56H66N14O4 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 1113.26 g/mol gives Osimertinib Impurity 104 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Osimertinib Impurity 104 (CAS CATO-C4X-2045104) is a certified pharmaceutical impurity reference standard with the molecular formula C56H66N14O4C2HF3O2 and a molecular weight of 1113.26 g/mol.
Structurally, Osimertinib Impurity 104 (C56H66N14O4C2HF3O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 31.0, corresponding to approximately 31 ring(s) or double-bond equivalent(s). With a molecular weight of 1113.26 g/mol, it falls into the high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Osimertinib Impurity 104 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C56H66N14O4 3*C2HF3O2 |
| Molecular Weight | 1113.26 g/mol |
| Purity | 95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 31.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 14 |
Related Osimertinib Standards
- Osimertinib Impurity 5 (CAS 1009298-59-2)
- Osimertinib Impurity 8 (CAS 1421372-66-8)
- Osimertinib Impurity N1 (CAS 1421372-67-9)
- Osimertinib Impurity N2 (CAS 1421373-36-5 (free base))
- Osimertinib (CAS 1421373-65-0)
- Osimertinib Impurity 10 (CAS 1421373-98-9)
- Osimertinib Impurity N3 (CAS 1421373-99-0)
- Osimertinib-3 (CAS 1446700-26-0)
Recommended Standards
- Cenobamate impurity 6 (CAS 913088-81-0)
- Lorazepam Impurity 19 (CAS CATO-C4X-104119)
- Selexipag Impurity 2 (CAS 475085-57-5)
- 7-Chlorothieno[3,2-b]pyridine oxalate (CAS 1187830-60-9)
- 4-(1-Methyl-5-nitro-1H-benzo[d]imidazol-2-yl)aniline (CAS 88203-30-9)
- n-(Cyclohexylmethyl)-2-methylbutan-2-amine (CAS 932159-89-2)
- 1-((5-Bromo-2-methylphenyl)sulfonyl)pyrrolidine (CAS 1178386-07-6)
- Antipyrine Impurity 3 (CAS 1430813-66-3)
- (S)-(2-Amino-3,3-dimethylbutanoyl)glycine (CAS 98035-62-2)
- Delicious Peptide (bovine) (CAS 73984-05-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com