Dasatinib Impurity 27 CAS CATO-C4X-204527
| CAS No. | CATO-C4X-204527 |
| Molecular Formula | C22H26ClN7O2S |
| Molecular Weight | 488.01 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Dasatinib Impurity 27 (CAS CATO-C4X-204527) is a certified pharmaceutical impurity reference standard with the molecular formula C22H26ClN7O2S and a molecular weight of 488.01 g/mol.
Owing to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution, Dasatinib Impurity 27 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 488.01 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H26ClN7O2S |
| Molecular Weight | 488.01 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 7 |
| Sulfur Atoms | 1 |
Related Dasatinib Standards
- Dasatinib (CAS 302962-49-8)
- Dasatinib Impurity 31 (CAS CATO-C4X-160731)
- Dasatinib Impurity 32 (CAS 2468737-83-7)
- Dasatinib Impurity 36 (CAS 2048106-50-7)
- Dasatinib Impurity 70 (CAS CATO-C4X-160770)
- Dasatinib Impurity 76 (CAS CATO-C4X-160776)
- Dasatinib Impurity 28 (CAS CATO-C4X-204528)
- Dasatinib D4 (CAS 1160297-08-4)
Recommended Standards
- Amidotrizoic Acid EP Impurity B (CAS 162193-52-4)
- Amidotrizoic Acid Dihydrate - Impurity C (CAS 162193-53-5)
- Valemetostat (CAS 1809336-39-7)
- Rupatadine Impurity 35 (CAS 1632412-57-7)
- Capivasertib Impurity 1 (CAS 1143532-51-7)
- Lifitegrast Impurity 161 (CAS CATO-C4X-2409161)
- Aztreonam Impurity 1 (CAS 80082-65-1)
- 5-[[(4-Fluorophenyl)methyl]amino]-1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-one- d4 (CAS 1346598-41-1)
- (1-propyl-1H-pyrrol-3-yl)methanamine (CAS 1512560-72-3)
- Loratadine EP Impurity D (CAS 100643-71-8)
- (2E,5E)-2,5-bis((hydroxymethoxy)methylene)furan-3,4(2H,5H)-dione (CAS 2004-74-2)
- Benzyl 7-((tert-butoxycarbonyl)amino)-5-azaspiro[2.4]Heptane-5-carboxylate (CAS 1268451-83-7)
- Tetraethyl Thionopyrophosphate (CAS 645-78-3)
- Semaglutide impurity 48 (CAS CATO-C4X-222648)
Why CATO?
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- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com