Bictegravir-15N, d2 CAS CATO-C4X-21811
| CAS No. | CATO-C4X-21811 |
| Molecular Formula | C21H16D2F3N2[15N]O5 |
| Molecular Weight | 452.39 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Bictegravir-15N, d2.
CATO supplies Bictegravir-15N, d2 (CAS CATO-C4X-21811), a certified reference material (molecular formula C21H16D2F3N2[15N]O5, MW 452.39 g/mol) for analytical method development and quality control.
The molecular framework of Bictegravir-15N, d2 (C21H16D2F3N2[15N]O5) is characterized by deuterium isotope labeling, a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures Bictegravir-15N, d2 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H16D2F3N2[15N]O5 |
| Molecular Weight | 452.39 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Bictegravir Standards
- Bictegravir (CAS 1611493-60-7)
- Bictegravir Impurity 10(2R,5S,13aS) (CAS CATO-C4X-218110)
- Bictegravir Impurity 8(2S,5R,13aS) (CAS CATO-C4X-21818)
- Bictegravir Impurity 9(2R,5R,13aR) (CAS CATO-C4X-21819)
- Bictegravir Related Compound C001/Dolutegravir Intermediate-1 (CAS 1335210-23-5)
- Bictegravir Impurity 2 (CAS CATO-C4X-21812)
- Bictegravir Related Compound 2 (CAS 1110772-05-8)
- Bictegravir impurity 11 (CAS CATO-C4X-218111)
Recommended Standards
- N-(4-Bromophenyl)-2-((3-ethyl-5,6-dimethyl-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)thio)acetamide (CAS 618427-66-0)
- Ethyl 4-((6-(benzo[d][1,3]dioxol-5-yl)-3-cyano-4-(trifluoromethyl)pyridin-2-yl)thio)-3-oxobutanoate (CAS 625376-79-6)
- N-(3-Bromophenyl)-2-((3-ethyl-5,6-dimethyl-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)thio)acetamide (CAS 573948-54-6)
- Curculigoside B (CAS 143601-09-6)
- 6-Fluoro-4-(pyrrolidin-1-yl)-1,2,3,4-tetrahydroisoquinoline (CAS 1447962-44-8)
- Cyclopentyl 4-(thiomorpholinomethyl)phenyl ketone (CAS 898783-32-9)
- 2-fluoro-5-methylpyridine-4-boronic acid (CAS 929194-41-2)
- 1-(4-Fluorophenyl)-2-[(2-{[2-(4-fluorophenyl)-2-oxoethyl]sulfanyl}ethyl)sulfanyl]ethan-1-one (CAS 271772-52-2)
- (2-{2-[2-(2-aminoethyl)-4,5-dimethoxybenzyl]-4,5-dimethoxyphenyl}ethyl)amine dihydrochloride (CAS 1328085-12-6)
- 2-(4-Methoxyphenyl)-N-(5-oxo-2,3,4,5-tetrahydrobenzo[f][1,4]oxazepin-7-yl)acetamide (CAS 922056-04-0)
- 2-(5-Amino-2-methoxyphenoxy)acetamide (CAS 954562-31-3)
- n-(Piperidin-4-ylmethyl)picolinamide (CAS 727661-47-4)
- 8-(Difluoromethyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)quinoline (CAS 2818959-20-3)
- Des-Pro36-Tirzepatide (CAS CATO-CPTD788937)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com