Bictegravir Impurity 2 CAS CATO-C4X-21812
| CAS No. | CATO-C4X-21812 |
| Molecular Formula | C14H9F6N |
| Molecular Weight | 305.22 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 305.22 g/mol gives Bictegravir Impurity 2 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Bictegravir Impurity 2 (CAS CATO-C4X-21812, C14H9F6N) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Bictegravir Impurity 2 (C14H9F6N) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 305.22 g/mol, it falls into the moderately-high-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Bictegravir Impurity 2 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H9F6N |
| Molecular Weight | 305.22 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Bictegravir Standards
- Bictegravir Related Compound C001/Dolutegravir Intermediate-1 (CAS 1335210-23-5)
- Bictegravir (CAS 1611493-60-7)
- Bictegravir Impurity 10(2R,5S,13aS) (CAS CATO-C4X-218110)
- Bictegravir Impurity 8(2S,5R,13aS) (CAS CATO-C4X-21818)
- Bictegravir Impurity 9(2R,5R,13aR) (CAS CATO-C4X-21819)
- Bictegravir-15N, d2 (CAS CATO-C4X-21811)
- Bictegravir Related Compound 2 (CAS 1110772-05-8)
- Bictegravir impurity 11 (CAS CATO-C4X-218111)
Recommended Standards
- N-Phenyl-3,5-bis(trifluoromethyl)aniline (CAS 23917-96-6)
- 4-bromo-N-[2-(methylsulfanyl)ethyl]-1-(propan-2-yl)-1H-pyrrole-2-carboxamide (CAS 1184272-57-8)
- N,N-Dimethyl-3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy)propan-1-amine (CAS 627899-90-5)
- 2-(((5-Bromothiophen-2-yl)methyl)(ethyl)amino)-N-ethylacetamide (CAS 1240855-62-2)
- Phenylephrine Impurity 100 (CAS 1026633-55-5)
- Azithromycin Impurity 23 (CAS CATO-C4X-100323)
- Polydatin Impurity 1 (CAS 3009113-18-9)
- (R)-1-(tert-butoxycarbonyl)-2-(2-(trifluoromethyl)benzyl)pyrrolidine-2-carboxylic acid (CAS 959576-51-3)
- 3-(tert-Butyl)-5-(cyclopropylmethyl)phenol (CAS 1243408-33-4)
- (3S,4R,5S,6S)-6-Methyltetrahydro-2H-pyran-2,3,4,5-tetraol (CAS 87-96-7)
- 2-Amino-4-(4-isobutylphenyl)thiophene-3-carbonitrile (CAS 438218-65-6)
- 2-Formyl-4-methyl-1H-pyrrole-3-carbonitrile (CAS 1380521-11-8)
- N-(5-Amino-2-methylphenyl)-4-(2-methoxyethoxy)-benzamide (CAS 1020054-16-3)
- Insulin Pork(≥27 USP units/mg) (CAS 12584-58-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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