Roxadustat Impurity 125 CAS CATO-C4X-2213125
| CAS No. | CATO-C4X-2213125 |
| Molecular Formula | C23H22N4O7 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
As a process- or degradation-related impurity, Roxadustat Impurity 125 (CAS CATO-C4X-2213125, C23H22N4O7C2HF3O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C23H22N4O7C2HF3O2, Roxadustat Impurity 125 contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 580.47 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C23H22N4O7 C2HF3O2 |
| Molecular Weight | 580.47 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Roxadustat Standards
- Roxadustat Impurity N6 (CAS 1421312-32-4)
- Roxadustat Impurity N4 (CAS 1421312-33-5)
- Roxadustat Impurity N3 (CAS 1421312-34-6)
- Roxadustat Impurity 9 (CAS 1421312-35-7)
- Roxadustat Impurity 5 (CAS 1421312-36-8)
- Roxadustat Impurity 33 (CAS 1455091-04-9)
- Roxadustat Impurity 7 (CAS 1455091-06-1)
- Roxadustat Impurity N15 (CAS 1455091-10-7)
Recommended Standards
- Diclofenac Impurity 25 (CAS CATO-C4X-105125)
- Anastrozole Impurity 34 (CAS CATO-C4X-123934)
- Epinastine Impurity 8 (CAS CATO-C4X-18408)
- Isobutyl p-methyl Benzenesulfonic acid (CAS 4873-56-7)
- (3-(6-Fluoropyridin-2-yl)phenyl)boronic acid (CAS 2225175-43-7)
- 1-acetylpyrrolidine-2-carbaldehyde (CAS 73323-64-5)
- 5-(2-Chloroacetamido)-4-cyano-3-methylthiophene-2-carboxamide (CAS 908518-23-0)
- Spinetoram J (CAS 187166-40-1)
- Bis(4-methoxyphenyl) furan-2,4-dicarboxylate (CAS 57467-49-9)
- Semaglutide impurity 86 (CAS CATO-C4X-222686)
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