Roxadustat Impurity 161 CAS CATO-C4X-2213161
| CAS No. | CATO-C4X-2213161 |
| Molecular Formula | C14H9ClO3 |
| Molecular Weight | 260.67 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Roxadustat Impurity 161 (CAS CATO-C4X-2213161) is a certified pharmaceutical impurity reference standard with the molecular formula C14H9ClO3 and a molecular weight of 260.67 g/mol.
The molecular framework of Roxadustat Impurity 161 (C14H9ClO3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Roxadustat Impurity 161 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H9ClO3 |
| Molecular Weight | 260.67 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
Related Roxadustat Standards
- Roxadustat Impurity 81 (CAS CATO-C4X-221381)
- Roxadustat Impurity 41 (CAS CATO-C4X-221341)
- Roxadustat Impurity 157 (CAS CATO-C4X-2213157)
- Roxadustat Impurity 116 (CAS CATO-C4X-2213116)
- Roxadustat Impurity 79 (CAS CATO-C4X-221379)
- Roxadustat Impurity 159 (CAS CATO-C4X-2213159)
- Roxadustat Impurity 33 (CAS 1455091-04-9)
- Roxadustat Impurity 42 (CAS CATO-C4X-221342)
Recommended Standards
- Zidovudine EP Impurity B (CAS 25526-94-7)
- Chlorflurenol (CAS 2464-37-1)
- Chlorthalidone Impurity N1 (CAS 5543-24-8)
- 10-Chloro-3,4-dihydro-2h-[1,4]dioxepino[2,3-g]quinoline-9-carbonitrile (CAS 1017037-61-4)
- Linezolid Impurity 109 (CAS CATO-C4X-1073109)
- Glucosamine sulfate impurity 24 (CAS 6082-29-7)
- Sunitinib Impurity 81 (CAS CATO-C4X-133381)
- PF-5274857 hydrochloride, >98% (HPLC) (CAS 1613439-62-5)
- 3-Iodo-1-isopropyl-1H-pyrrolo[3,2-c]pyridine (CAS 1597421-43-6)
- Ethyl 5,5-dimethylhexanoate (CAS 104093-22-3)
- bietamiverin (CAS 479-81-2)
- Tert-butyl 3-(methylcarbamoyl)piperazine-1-carboxylate (CAS 1361111-44-5)
- 2-(4-ethylphenyl)acetaldehyde (CAS 68083-54-5)
- Semaglutide Sodium Salt (CAS CATO-C4X-222620)
Why CATO?
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- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com