Roxadustat Impurity 32 Formate CAS CATO-C4X-221332
| CAS No. | CATO-C4X-221332 |
| Molecular Formula | C21H19N3O7 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Roxadustat Impurity 32 Formate (CAS CATO-C4X-221332, C21H19N3O7CH2O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Roxadustat Impurity 32 Formate (C21H19N3O7CH2O2) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 14.0, corresponding to approximately 14 ring(s) or double-bond equivalent(s). With a molecular weight of 471.42 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Roxadustat Impurity 32 Formate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H19N3O7 CH2O2 |
| Molecular Weight | 471.42 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 3 |
Related Roxadustat Standards
- Roxadustat Impurity N6 (CAS 1421312-32-4)
- Roxadustat Impurity N4 (CAS 1421312-33-5)
- Roxadustat Impurity N3 (CAS 1421312-34-6)
- Roxadustat Impurity 9 (CAS 1421312-35-7)
- Roxadustat Impurity 5 (CAS 1421312-36-8)
- Roxadustat Impurity 33 (CAS 1455091-04-9)
- Roxadustat Impurity 7 (CAS 1455091-06-1)
- Roxadustat Impurity N15 (CAS 1455091-10-7)
Recommended Standards
- Isavuconazole Impurity 110 (CAS CATO-C4X-1236110)
- Ivabradine Impurity 53 (CAS CATO-C4X-111953)
- Febantel EP Impurity B (CAS 92114-71-1)
- JWH-203 Impurity 2（JWH 203 3-Chloro Isomer） (CAS 864445-56-7)
- (2E)-3-Amino-3-(4-methylphenyl)prop-2-enenitrile (CAS 17196-75-7)
- 3,7-dihydro-7-(3-methylbutyl)-3-(phenylmethyl)-1H-Purine-2,6-dione, potassium salt (1:1) (CAS 1052541-60-2)
- Arylpyrazol (CAS 121750-17-2)
- Liraglutide Impurity 31 (CAS CATO-C4X-199231)
- Benzofuran-7-carbaldehyde (CAS 95333-14-5)
- D-Ser39-Tirzepatide (CAS CATO-CPTD788694)
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