Roxadustat Impurity 85 CAS CATO-C4X-221385
| CAS No. | CATO-C4X-221385 |
| Molecular Formula | C19H16N2O4 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Roxadustat Impurity 85.
CATO supplies Roxadustat Impurity 85 (CAS CATO-C4X-221385), a pharmacopoeial impurity reference standard (molecular formula C19H16N2O4HCl, MW 372.80 g/mol) used for the identification and quantification of trace impurities in APIs.
Roxadustat Impurity 85 (C19H16N2O4HCl) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Roxadustat Impurity 85 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H16N2O4 HCl |
| Molecular Weight | 372.80 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Roxadustat Standards
- Roxadustat Impurity N6 (CAS 1421312-32-4)
- Roxadustat Impurity N4 (CAS 1421312-33-5)
- Roxadustat Impurity N3 (CAS 1421312-34-6)
- Roxadustat Impurity 9 (CAS 1421312-35-7)
- Roxadustat Impurity 5 (CAS 1421312-36-8)
- Roxadustat Impurity 33 (CAS 1455091-04-9)
- Roxadustat Impurity 7 (CAS 1455091-06-1)
- Roxadustat Impurity N15 (CAS 1455091-10-7)
Recommended Standards
- Netupitant Impurity 51 (CAS CATO-C4X-122351)
- Palbociclib Impurity 179 (CAS CATO-C4X-1125179)
- Ibrutinib Impurity 88 (CAS 2417548-83-3)
- 5-Chloro-2-(oxolan-3-yloxy)benzonitrile (CAS 1375471-48-9)
- 3-Bromo-2-(pentyloxy)pyridine (CAS 1247796-74-2)
- 1,5-diphenylpentan-1-amine (CAS 21493-12-9)
- Lemborexant Impurity 66 (CAS 1450905-00-6)
- Ethyl 1-(3-chloro-4-fluorophenyl)-4-hydroxy-1H-pyrazole-3-carboxylate (CAS 379241-53-9)
- 3-(3-Bromo-4-methoxyphenyl)-2-methylpropanoic acid (CAS 156417-81-1)
- [Glu]17-Semaglutide (CAS CATO-CPTD788604)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com