Avatrombopag impurity 133 CAS CATO-C4X-2234133
| CAS No. | CATO-C4X-2234133 |
| Molecular Formula | C25H30Cl2N6OS2 |
| Molecular Weight | 565.58 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution, Avatrombopag impurity 133 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 565.58 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies Avatrombopag impurity 133 (CAS CATO-C4X-2234133), a pharmacopoeial impurity reference standard (molecular formula C25H30Cl2N6OS2, MW 565.58 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C25H30Cl2N6OS2 |
| Molecular Weight | 565.58 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 6 |
| Sulfur Atoms | 2 |
Related Avatrombopag Standards
- Avatrombopag Impurity 1 (CAS 2626934-45-8)
- Avatrombopag Impurity 7 (CAS CATO-C4X-22347)
- Avatrombopag Impurity 101 (CAS CATO-C4X-2234101)
- Avatrombopag Impurity 62 (CAS 570403-04-2)
- Avatrombopag Impurity 82 (CAS CATO-C4X-223482)
- Avatrombopag Impurity 12 (CAS 762237-66-1)
- Avatrombopag Impurity 141 (CAS 570403-05-3)
- Avatrombopag Impurity 105 (CAS CATO-C4X-2234105)
Recommended Standards
- Lasmiditan Impurity 70 (CAS CATO-C4X-247870)
- N-Benzoyl-N-(8-(benzyloxy)-9-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-yl)benzamide (CAS 142979-39-3)
- Ceftizoxime Impurity 24 (CAS 929101-91-7)
- Z-Gly-Ala-Gln-AMC (CAS 201928-35-0)
- Glutathione Impurity 11 (CAS CATO-C4X-118511)
- Amlodipine Impurity 113 (CAS CATO-C4X-1095113)
- Tulobuterol Impurity 23 (CAS CATO-C4X-213423)
- 4-(tert-Butyl)-2-cyclopropoxy-1-isopropoxybenzene (CAS 1243373-32-1)
- Methyl 5-chlorobenzofuran-2-carboxylate (CAS 4852-31-7)
- 1-(2-Bromophenyl)-2-(trifluoromethoxy)ethan-1-one (CAS 1334149-33-5)
- 2-(5-Chlorothiophen-2-yl)-8-methylquinoline-4-carboxylic acid (CAS 438229-02-8)
- Disermolide (CAS 127943-53-7)
- N-Acetyl-DL-aspartic-2,3,3-d3 Acid (CAS 89829-69-6)
- Liraglutide (13-21) TFA Salt (CAS CATO-C4X-19928)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com