Avatrombopag Impurity 44 CAS 570407-63-5
| CAS No. | 570407-63-5 |
| Molecular Formula | C17H22Cl2N4S2 |
| Molecular Weight | 417.42 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Avatrombopag Impurity 44.
CATO supplies Avatrombopag Impurity 44 (CAS 570407-63-5), a pharmacopoeial impurity reference standard (molecular formula C17H22Cl2N4S2, MW 417.42 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Avatrombopag Impurity 44 (C17H22Cl2N4S2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 417.42 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Avatrombopag Impurity 44 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H22Cl2N4S2 |
| Molecular Weight | 417.42 g/mol |
| Purity | >95% |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 2 |
Related Avatrombopag Standards
- Avatrombopag Impurity 34 (CAS CATO-C4X-223434)
- Avatrombopag Impurity 77 (CAS CATO-C4X-223477)
- Avatrombopag Impurity 13 (CAS CATO-C4X-223413)
- Avatrombopag Impurity 64 (CAS CATO-C4X-223464)
- Avatrombopag Impurity 98 (CAS CATO-C4X-223498)
- Avatrombopag Impurity 63 (CAS CATO-C4X-223463)
- Avatrombopag Impurity 109 (CAS CATO-C4X-2234109)
- Avatrombopag impurity 132 (CAS CATO-C4X-2234132)
Recommended Standards
- Tryptophan impurity 40 (CAS CATO-C4X-137340)
- Atogepant Impurity 78 (CAS 1488326-89-1)
- Tryptophan impurity 39 (CAS CATO-C4X-137339)
- Methyl 3-cyclopropyl-1-(4-fluorophenyl)-6-(4-methoxyphenyl)-1h-pyrazolo[3,4-b]pyridine-4-carboxylate (CAS 1011398-35-8)
- Pitavastatin Impurity 102 (CAS CATO-C4X-1037102)
- Apremilast Impurity 98 (CAS CATO-C4X-100998)
- Betamethasone impurity 67 (CAS 13796-49-1)
- 2-Chloro-3-(dimethoxymethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (CAS 1315341-84-4)
- 6-(4-Amino-1,2,5-oxadiazol-3-yl)-1,3,5-triazine-2,4-diamine (CAS 309922-32-5)
- Methyl 2-amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylate (CAS 1638768-39-4)
- beta-Glycerylphosphorylcholine (CAS 18418-25-2)
- 3-Nitroaniline (CAS 99-09-2)
- Hydrochlorothiazide Impurity 23 (CAS 19477-32-8)
- Amyloid Precursor Frameshift Mutant C-Terminal Peptide trifluoroacetate salt (CAS 189125-14-2)
Why CATO?
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