Avatrombopag Impurity 77 CAS CATO-C4X-223477
| CAS No. | CATO-C4X-223477 |
| Molecular Formula | C17H23BrN4S2 |
| Molecular Weight | 427.43 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Avatrombopag Impurity 77 (CAS CATO-C4X-223477), a pharmacopoeial impurity reference standard (molecular formula C17H23BrN4S2, MW 427.43 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, bromine substitution, Avatrombopag Impurity 77 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 427.43 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Avatrombopag Impurity 77 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H23BrN4S2 |
| Molecular Weight | 427.43 g/mol |
| Purity | >95% |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 2 |
Related Avatrombopag Standards
- Avatrombopag Impurity 34 (CAS CATO-C4X-223434)
- Avatrombopag Impurity 13 (CAS CATO-C4X-223413)
- Avatrombopag Impurity 64 (CAS CATO-C4X-223464)
- Avatrombopag Impurity 98 (CAS CATO-C4X-223498)
- Avatrombopag Impurity 44 (CAS 570407-63-5)
- Avatrombopag Impurity 106 (CAS CATO-C4X-2234106)
- Avatrombopag Impurity 79 (CAS CATO-C4X-223479)
- Avatrombopag Impurity 63 (CAS CATO-C4X-223463)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com