Ponatinib Impurity 13 CAS CATO-C4X-226913
| CAS No. | CATO-C4X-226913 |
| Molecular Formula | C21H23F6N3 |
| Molecular Weight | 431.42 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Ponatinib Impurity 13.
CATO supplies Ponatinib Impurity 13 (CAS CATO-C4X-226913), a pharmacopoeial impurity reference standard (molecular formula C21H23F6N3, MW 431.42 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Ponatinib Impurity 13 (C21H23F6N3) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 431.42 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Ponatinib Impurity 13 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H23F6N3 |
| Molecular Weight | 431.42 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | ≥95% |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Ponatinib Standards
- Ponatinib Impurity 33 (CAS CATO-C4X-226933)
- Ponatinib Impurity 53 (CAS CATO-C4X-226953)
- Ponatinib Impurity N72 (CAS 957147-18-1)
- Ponatinib Impurity 60 (CAS CATO-C4X-226960)
- Ponatinib Impurity 42 (CAS CATO-C4X-226942)
- Ponatinib Impurity 20 (CAS CATO-C4X-226920)
- Ponatinib Impurity 31 (CAS CATO-C4X-226931)
- Ponatinib Impurity 9 (CAS CATO-C4X-22699)
Recommended Standards
- Relebactam Impurity 87 (CAS 2540656-36-6)
- Fmoc-Glu(α-O<I>t</I>Bu)-OH-<SUP>13</SUP>C<SUB>5</SUB>,<SUP>15</SUP>N (CAS 1628109-77-2)
- 2-(3-(3,7-Dioxo-6-phenyl-3,7-dihydro-2H-thiazolo[3,2-b][1,2,4]triazin-2-ylidene)-2-oxoindolin-1-yl)acetamide (CAS 607385-13-7)
- N-(3-((6-Acetamidopyridin-3-yl)oxy)phenyl)-2-oxo-3-phenylimidazolidine-1-carboxamide (CAS 1020536-03-1)
- Roxadustat Impurity 60 (CAS CATO-C4X-221360)
- Lincomycin EP Impurity E (CAS 13380-36-4)
- Neratinib Impurity 12 (CAS 1144516-18-6)
- (5-(4-Fluorophenyl)isoxazol-3-yl)methanamine (CAS 1018604-92-6)
- 2-(2-Chloropyridin-3-yl)propan-2-ol (CAS 267003-35-0)
- (5-methylpyridazin-4-yl)methanol (CAS 1956324-99-4)
- 2-Heptyl Hydroperoxide (CAS 762-46-9)
- 4-(5-Bromo-1H-imidazol-2-yl)pyridine (CAS 1260682-35-6)
- 5-Bromo-1-methyl-6-(trifluoromethyl)-1H-indole (CAS 1649953-47-8)
- Neuropeptide Y (human, rat) trifluoroacetate salt (CAS 90880-35-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com