Ponatinib Impurity 42 CAS CATO-C4X-226942
| CAS No. | CATO-C4X-226942 |
| Molecular Formula | C9H8I2O2 |
| Molecular Weight | 401.97 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Ponatinib Impurity 42 (CAS CATO-C4X-226942, C9H8I2O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C9H8I2O2, Ponatinib Impurity 42 contains a carboxylic acid group, a hydroxyl group, an ether linkage, iodine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 401.97 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Ponatinib Impurity 42 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H8I2O2 |
| Molecular Weight | 401.97 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | ≥95% |
| Storage | Store at room temperature |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | I-containing |
Related Ponatinib Standards
- Ponatinib Impurity 31 (CAS CATO-C4X-226931)
- Ponatinib Impurity 9 (CAS CATO-C4X-22699)
- Ponatinib Impurity N72 (CAS 957147-18-1)
- Ponatinib Impurity 45 (CAS CATO-C4X-226945)
- Ponatinib Impurity 13 (CAS CATO-C4X-226913)
- Ponatinib Impurity 33 (CAS CATO-C4X-226933)
- Ponatinib impurity 5 (CAS 122947-77-7)
- Ponatinib Impurity 19 (CAS CATO-C4X-226919)
Recommended Standards
- Ethyl 3,5-diiodobenzoate (CAS 388613-52-3)
- (E)-4,5,5,6,6,6-hexafluoro-2-iodo-4-(trifluoromethyl)hex-2-en-1-ol (CAS 261503-77-9)
- 4-Ethoxy-3,5-diiodobenzaldehyde (CAS 632299-37-7)
- 2,2'-Dibromo-5,5'-dinitrobiphenyl (CAS 52026-22-9)
- Vaborbactam Impurity 3 (CAS CATO-C4X-34773)
- Estradiol Impurity 23 (CAS 1093411-48-3)
- Cloperastine Impurity 5 HCl (CAS CATO-C4X-15955)
- 4-(4-Cyclohexylphenyl)-4-oxo-2-{[(pyridin-3-yl)methyl]amino}butanoic acid (CAS 329929-06-8)
- 5-Methyl-2-nitro-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine (CAS 1227210-32-3)
- 2-(Tert-butylsulfamoyl)acetic acid (CAS 1042628-75-0)
- 4-[2-(2-Chloro-4-ethylphenoxy)ethyl]piperidinehydrochloride (CAS 1220029-35-5)
- Methyl 3-bromo-5-cyano-2-methylbenzoate (CAS 1806061-00-6)
- N-(4-chlorobenzyl)-2-(2-phenylacetyl)benzamide (CAS 329079-84-7)
- Gastric Inhibitory Polypeptide (3-42) (human) trifluoroacetate salt (CAS 1802086-25-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com