Ponatinib Impurity 34 CAS CATO-C4X-226934
| CAS No. | CATO-C4X-226934 |
| Molecular Formula | C16H14F6N2 |
| Molecular Weight | 348.29 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Ponatinib Impurity 34 is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Ponatinib Impurity 34 (CAS CATO-C4X-226934), a pharmacopoeial impurity reference standard (molecular formula C16H14F6N2, MW 348.29 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution, Ponatinib Impurity 34 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 348.29 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Ponatinib Impurity 34 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H14F6N2 |
| Molecular Weight | 348.29 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Ponatinib Standards
- Ponatinib Impurity 16 (CAS CATO-C4X-226916)
- Ponatinib Impurity 19 (CAS CATO-C4X-226919)
- Ponatinib impurity 5 (CAS 122947-77-7)
- Ponatinib Impurity 45 (CAS CATO-C4X-226945)
- Ponatinib Impurity 31 (CAS CATO-C4X-226931)
- Ponatinib Impurity 9 (CAS CATO-C4X-22699)
- Ponatinib Impurity 47 (CAS CATO-C4X-226947)
- Ponatinib Impurity 48 (CAS CATO-C4X-226948)
Recommended Standards
- 1,1＇-Binaphthyl-2,2＇-diyl hydrogenphosphate (CAS 35193-63-6)
- 2,3,4,6-Tetra-O-acetyl-D-glucopyranose (CAS 10343-06-3)
- Tamsulosin Impurity 13 (CAS 35193-64-7)
- Methyl 3,4-Di-O-acetyl-b-L-idopyranosiduronate 1,2-(Methylorthoacetate) (CAS 107952-66-9)
- Creatine Phosphate Impurity 11 (CAS CATO-C4X-120911)
- Cinacalcet Impurity 27 (CAS 851984-49-1 (free base))
- Imidapril Impurity 15 (CAS 157085-06-8(free base))
- 1-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(hydroxymethyl)cyclobutane-1-carboxylic acid (CAS 2219374-93-1)
- 3-(2-Bromoacetyl)pyridin-2(1H)-one (CAS 27038-46-6)
- 6-Chloro-N-(1-methyl-1h-pyrazol-5-yl)pyridine-3-carboxamide (CAS 1250312-35-6)
- S-(Oxetan-3-yl) ethanethioate (CAS 1402428-24-3)
- Zopiclone Impurity 19 (CAS CATO-C4X-123819)
- 2-(1H-Pyrazol-1-yl)acetamide (CAS 113336-24-6)
- Semaglutide Impurity 142 (CAS CATO-C4X-2226142)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com