Lifitegrast Impurity 25 CAS CATO-C4X-240925
| CAS No. | CATO-C4X-240925 |
| Molecular Formula | C26H23NO6S |
| Molecular Weight | 477.53 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Lifitegrast Impurity 25 (CAS CATO-C4X-240925) is a certified pharmaceutical impurity reference standard with the molecular formula C26H23NO6S and a molecular weight of 477.53 g/mol.
Lifitegrast Impurity 25 (C26H23NO6S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. The carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C26H23NO6S |
| Molecular Weight | 477.53 g/mol |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Lifitegrast Standards
- Lifitegrast Impurity 158 (CAS CATO-C4X-2409158)
- Lifitegrast Impurity 170 (CAS CATO-C4X-2409170)
- Lifitegrast Impurity 156 (CAS CATO-C4X-2409156)
- Lifitegrast Impurity 157 (CAS CATO-C4X-2409157)
- Lifitegrast Impurity N12 (CAS 851785-70-1)
- Lifitegrast Impurity 69 (CAS CATO-C4X-240969)
- Lifitegrast impurity 92 (CAS CATO-C4X-240992)
- Lifitegrast Impurity 37 (CAS 1194550-56-5)
Recommended Standards
- Phthalimide-PEG3-C2-OTs (CAS 382162-12-1)
- 4-Tosyl Mycophenolic Acid-d (CAS 1185242-13-0)
- N,N-Dibenzyl-1-(4-fluorobenzyl)-2-oxo-1,2-dihydro-1,8-naphthyridine-3-carboxamide (CAS 923173-06-2)
- 4-(5-(6-(Benzylthio)-9H-purin-9-yl)pentanamido)-2-hydroxybenzoic acid (CAS 4369-82-8)
- Suvorexant Impurity 36 (CAS CATO-C4X-181236)
- Brivaracetam Impurity 59 (CAS CATO-C4X-200759)
- Phenylephrine Impurity 71 (CAS CATO-C4X-146771)
- 4,5-Dibromo-3-(difluoromethyl)-2-fluoropyridine (CAS 1806878-32-9)
- 7-Fluoro-2,3-dihydrobenzofuran-3-amine (CAS 939757-42-3)
- N-(4-Isopropyl-2-(3-oxo-3,4-dihydroquinoxalin-2-yl)phenyl)thiophene-2-carboxamide (CAS 1404437-62-2)
- N-(4-Fluorophenyl)-4-methylbenzenesulfonamide (CAS 727-31-1)
- N,N-Dicarboxymethyl-N,N-dinitroso-p-phenylenediamine, disodium salt (CAS 1042969-16-3)
- Riluzole Impurity 14 (CAS CATO-C4X-200914)
- Casein Kinase II Receptor Peptide (CAS 198481-81-1)
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