Venetoclax Impurity 141 CAS CATO-C4X-2495141
| CAS No. | CATO-C4X-2495141 |
| Molecular Formula | C49H60ClN9O6S |
| Molecular Weight | 938.58 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Venetoclax Impurity 141 (C49H60ClN9O6S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a process- or degradation-related impurity, Venetoclax Impurity 141 (CAS CATO-C4X-2495141, C49H60ClN9O6S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Venetoclax Impurity 141 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C49H60ClN9O6S |
| Molecular Weight | 938.58 g/mol |
| Purity | ≥95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 24.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 9 |
| Sulfur Atoms | 1 |
Related Venetoclax Standards
- Venetoclax Impurity 23 (CAS CATO-C4X-249523)
- Venetoclax Impurity 82 (CAS CATO-C4X-249582)
- Venetoclax Impurity 83 (CAS CATO-C4X-249583)
- Venetoclax Impurity 22 (CAS CATO-C4X-249522)
- Venetoclax Impurity 47 (CAS CATO-C4X-249547)
- Venetoclax Impurity 60 (CAS CATO-C4X-249560)
- Venetoclax Nitroso Impurity 15 (CAS CATO-C4X-249515)
- Venetoclax Impurity 24 (CAS CATO-C4X-249524)
Recommended Standards
- Dibromo[μ-[1,1′-methylenebis[1,1-diphenylphosphine-κP]]]digold (CAS 72476-68-7)
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- Atosiban Impurity 94 (CAS CATO-C4X-229394)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com