Venetoclax Impurity 47 CAS CATO-C4X-249547
| CAS No. | CATO-C4X-249547 |
| Molecular Formula | C56H69ClN6O3 |
| Molecular Weight | 909.64 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Venetoclax Impurity 47 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Venetoclax Impurity 47 (CAS CATO-C4X-249547) is a certified pharmaceutical impurity reference standard with the molecular formula C56H69ClN6O3 and a molecular weight of 909.64 g/mol.
The molecular framework of Venetoclax Impurity 47 (C56H69ClN6O3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C56H69ClN6O3 |
| Molecular Weight | 909.64 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 25.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 6 |
Related Venetoclax Standards
- Venetoclax Impurity 60 (CAS CATO-C4X-249560)
- Venetoclax Nitroso Impurity 15 (CAS CATO-C4X-249515)
- Venetoclax Impurity 24 (CAS CATO-C4X-249524)
- Venetoclax Impurity 50 (CAS CATO-C4X-249550)
- Venetoclax Impurity 61 (CAS CATO-C4X-249561)
- Venetoclax Impurity 23 (CAS CATO-C4X-249523)
- Venetoclax Impurity 82 (CAS CATO-C4X-249582)
- Venetoclax Impurity 83 (CAS CATO-C4X-249583)
Recommended Standards
- (3aS,8aS)-4,4,8,8-Tetrakis[3,5-bis(1-methylethyl)phenyl]tetrahydro-2,2-dimethyl-6-phenyl-1,3-dioxolo[4,5-e][1,3,2]dioxaphosphepin (CAS 1422371-27-4)
- ((1,3,5-Triazine-2,4,6-triyl)tris(benzene-3,1-diyl))tris(diphenylphosphine oxide) (CAS 1646906-26-4)
- (3aR,8aR)-(-)-4,4,8,8-Tetrakis(3,5-di-i-propylphenyl)tetrahydro-2,2-dimethyl-6-phenyl-1,3-dioxolo[4,5-e]dioxaphosphepin (CAS 1361146-90-8)
- Boron, [(7R)-7-[[12-(3,5-dimethyl-1H-pyrrol-2-yl-κN)-12-(3,5-dimethyl-2H-pyrrol-2-ylidene-κN)-1-oxododecyl]oxy]-4-hydroxy-N,N,N-trimethyl-10-oxo-3,5,9-trioxa-4-phosphapentacosan-1-aminium 4-oxidato(2-)]difluoro-, (T-4)- (CAS 1246355-63-4)
- Crisaborole Impurity 8 (CAS CATO-C4X-20218)
- Morinidazole Impurity 32 (CAS CATO-C4X-219632)
- Tulobuterol Impurity 13 (CAS CATO-C4X-213413)
- 1,4-Dichloro-2-methylbenzene (CAS 19389-61-9)
- (3',4'-Dimethyl-[1,1'-biphenyl]-4-yl)methanol (CAS 885963-84-8)
- 3-(Benzo[d][1,3]dioxol-5-yl)isothiazole-4-carboxylic acid (CAS 67049-03-0)
- 201802-67-7 4-(Diphenylamino)benzeneboronic acid 4-(Diphenylamino)phenylboronic acid 4-(N,N-Diphenylamino)-1-phenylboronic acid 4-(N,N-Diphenylamino)phenylboronic acid 4-(N-Diphenylamino)phenylboronic acid Triphenylamine-4-boronic acid (CAS 201802-67-7)
- 1-(2-Methoxyethyl)-N-(prop-2-yn-1-yl)-1H-pyrazole-3-carboxamide (CAS 1707386-75-1)
- 5-(Cyclopenta-2,4-dien-1-ylidene)hexanoic acid (CAS 833447-36-2)
- Tirzepatide Impurity 44 (CAS CATO-C4X-324044)
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