Abemaciclib Impurity 6 CAS CATO-C4X-29376
| CAS No. | CATO-C4X-29376 |
| Molecular Formula | C26H25F3N6 |
| Molecular Weight | 478.51 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Abemaciclib Impurity 6 (C26H25F3N6) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies Abemaciclib Impurity 6 (CAS CATO-C4X-29376), a pharmacopoeial impurity reference standard (molecular formula C26H25F3N6, MW 478.51 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Abemaciclib Impurity 6 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C26H25F3N6 |
| Molecular Weight | 478.51 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 6 |
Related Abemaciclib Standards
- Abemaciclib Impurity 42 (CAS 1231930-57-6)
- Abemaciclib Impurity 136 (CAS CATO-C4X-2937136)
- Abemaciclib Impurity 141 (CAS CATO-C4X-2937141)
- Abemaciclib Impurity 142 (CAS CATO-C4X-2937142)
- Abemaciclib Impurity 178 (CAS 1942029-13-1)
- Abemaciclib Impurity 159 (CAS CATO-C4X-2937159)
- Abemaciclib Impurity 155 (CAS CATO-C4X-2937155)
- Abemaciclib Impurity 156 (CAS CATO-C4X-2937156)
Recommended Standards
- Tucatinib Impurity 34 (CAS CATO-C4X-260534)
- Triamcinolone Diacetate (CAS 67-78-7)
- Codeine-6-ß-D-glucuronide-D3 (CAS 219533-59-2)
- 4-Benzyl 5'-methyl 1'-tosyl-1H,1'H-[3,3'-bipyrrole]-4,5'-dicarboxylate (CAS 106674-01-5)
- Dapagliflozin dibromide impurity (CAS 1043252-56-7)
- Ciprofloxacin Impurity 32 (CAS CATO-C4X-136232)
- Sermorelin Impurity 2 (CAS CATO-C4X-23422)
- 7-Ethylhexahydro-1H-pyrazino[1,2-c]pyrimidin-6(2H)-one (CAS 121360-21-2)
- 1-Ethyl-4-methyl-N-(thietan-3-yl)pyrrolidin-3-amine (CAS 1851948-91-8)
- Evocalcet Impurity 68 (CAS CATO-C4X-248568)
- 5-(3,5-Dimethoxyphenyl)-1,3,4-oxadiazole-2-thiol (CAS 749902-08-7)
- (3-Bromophenyl)(6-chloropyridin-3-yl)methanone (CAS 1187165-79-2)
- 2-Methyl-2H-thiazolo[3,2-a]pyrimidin-5(3H)-one (CAS 41200-23-1)
- Peptide YY (13-36) (canine, mouse, porcine, rat) (CAS 86895-09-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com