Alectinib Impurity 37 CAS CATO-C4X-283637
| CAS No. | CATO-C4X-283637 |
| Molecular Formula | C26H22N3O |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Alectinib Impurity 37 (C26H22N3OI) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, iodine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies Alectinib Impurity 37 (CAS CATO-C4X-283637), a pharmacopoeial impurity reference standard (molecular formula C26H22N3OI, MW 519.38 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Alectinib Impurity 37 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C26H22N3O I |
| Molecular Weight | 519.38 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | ≥95% |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | I-containing |
| Nitrogen Atoms | 3 |
Related Alectinib Standards
- Alectinib Impurity 5 (CAS 1247119-83-0)
- Alectinib Impurity 1 (CAS 1256578-99-0)
- Alectinib Impurity 2 (CAS 1256579-06-2)
- Alectinib (CAS 1256580-46-7)
- Alectinib Impurity 4 (CAS 1256584-72-1)
- Alectinib Impurity 3 (CAS 1256584-73-2)
- Alectinib Impurity 10 (CAS 1256584-74-3)
- Alectinib Impurity 12 (CAS 1256584-77-6)
Recommended Standards
- Brivudine impurity 7 (CAS CATO-C4X-27587)
- Fluralaner Impurity 49 (CAS CATO-C4X-218049)
- Gadobutrol impurity 167 (CAS CATO-C4X-2120167)
- 1,3-Diphenylimidazolidine-2,4,5-trione (CAS 6488-59-1)
- N-(5-Methyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)pyridazine-3-carboxamide (CAS 2246811-70-9)
- 4-(tert-Butyl)-2-(pyrrolidin-2-yl)-1H-imidazole (CAS 1153104-89-2)
- [4-(2,4-Dichloro-phenyl)-thiazol-2-yl]-(2-methoxy-benzyl)-amine (CAS 565179-64-8)
- 3-[(5-ethyl-1,3,4-thiadiazol-2-yl)carbamoyl]propanoic acid (CAS 79888-40-7)
- Styrene-α-d1 (stabilized with hydroquinone) (CAS 1193-80-2)
- Semaglutide impurity 274 (CAS CATO-C4X-2226274)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com