Gefapixant Impurity 5 CAS CATO-C4X-28495

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-28495
Molecular FormulaC14H17ClN4O4S
Molecular Weight372.83 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Gefapixant Impurity 5 CAS CATO-C4X-28495 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 372.83 g/mol gives Gefapixant Impurity 5 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Gefapixant Impurity 5 (CAS CATO-C4X-28495) is a certified pharmaceutical impurity reference standard with the molecular formula C14H17ClN4O4S and a molecular weight of 372.83 g/mol.

Based on its molecular formula C14H17ClN4O4S, Gefapixant Impurity 5 contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 372.83 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

As a certified reference material (CRM), Gefapixant Impurity 5 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC14H17ClN4O4S
Molecular Weight372.83 g/mol
Purity>95%
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Halogen ContentCl-containing
Nitrogen Atoms4
Sulfur Atoms1

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